Tomonori Sugiura1, Yasuaki Dohi2, Yasuyuki Takagi3, Takashi Yokochi4, Naofumi Yoshikane5, Kenji Suzuki5, Takamasa Tomiishi5, Takashi Nagami5, Mitsunori Iwase6, Hiroyuki Takase7, Yoshihiro Seo8, Nobuyuki Ohte8. 1. Department of Cardiology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan; Health Support Center WELPO, Toyota Motor Corporation, Toyota, Japan. Electronic address: tomosugi@med.nagoya-cu.ac.jp. 2. Department of Internal Medicine, Faculty of Rehabilitation Sciences, Nagoya Gakuin University, Nagoya, Japan; Health Support Center WELPO, Toyota Motor Corporation, Toyota, Japan. 3. Health Support Center WELPO, Toyota Motor Corporation, Toyota, Japan; Toyota Memorial Hospital, Toyota, Japan. 4. Midtown Clinic Meieki, Nagoya, Japan; Health Support Center WELPO, Toyota Motor Corporation, Toyota, Japan. 5. Health Support Center WELPO, Toyota Motor Corporation, Toyota, Japan. 6. Toyota Memorial Hospital, Toyota, Japan. 7. Department of Internal Medicine, Enshu Hospital, Hamamatsu, Japan; Department of Cardiology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan. 8. Department of Cardiology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan.
Abstract
BACKGROUND: A body shape index (ABSI) is a novel anthropometric measure calculated using waist circumference (WC), body mass index (BMI), and body height. This study investigated the usefulness of ABSI to identify individuals with metabolic syndrome (MetS) and increased arterial stiffness in the middle-aged population. METHODS: Middle-aged workers who underwent periodic health check-ups and who were without previous cardiovascular events were enrolled (n = 10,182). In addition to ABSI, visceral fat area (VFA) was evaluated using computed tomography. Obesity and MetS were diagnosed on the basis of WC, VFA, and ABSI. Arterial stiffness was examined by measuring the cardio-ankle vascular index (CAVI). RESULTS: ABSI was significantly associated with CAVI in multivariable regression analysis. Logistic regression analysis revealed that ABSI was independently associated with the presence of MetS diagnosed on the basis of WC or VFA after adjustment for potential confounders, including BMI. Subjects with MetS diagnosed on the basis of each obesity index showed higher CAVI values than those without. Among subjects with MetS diagnosed on the basis of WC or VFA, those with MetS who met the definition of ABSI obesity showed significantly higher CAVI than those who did not. The other logistic regression analysis demonstrated that CAVI was independently associated with MetS defined on the basis of ABSI. CONCLUSIONS: ABSI was significantly associated with CAVI and the presence of MetS in the middle-aged population and helped to discriminate individuals with MetS and increased CAVI. ABSI could serve to identify individuals with MetS and increased arterial stiffness.
BACKGROUND: A body shape index (ABSI) is a novel anthropometric measure calculated using waist circumference (WC), body mass index (BMI), and body height. This study investigated the usefulness of ABSI to identify individuals with metabolic syndrome (MetS) and increased arterial stiffness in the middle-aged population. METHODS: Middle-aged workers who underwent periodic health check-ups and who were without previous cardiovascular events were enrolled (n = 10,182). In addition to ABSI, visceral fat area (VFA) was evaluated using computed tomography. Obesity and MetS were diagnosed on the basis of WC, VFA, and ABSI. Arterial stiffness was examined by measuring the cardio-ankle vascular index (CAVI). RESULTS: ABSI was significantly associated with CAVI in multivariable regression analysis. Logistic regression analysis revealed that ABSI was independently associated with the presence of MetS diagnosed on the basis of WC or VFA after adjustment for potential confounders, including BMI. Subjects with MetS diagnosed on the basis of each obesity index showed higher CAVI values than those without. Among subjects with MetS diagnosed on the basis of WC or VFA, those with MetS who met the definition of ABSI obesity showed significantly higher CAVI than those who did not. The other logistic regression analysis demonstrated that CAVI was independently associated with MetS defined on the basis of ABSI. CONCLUSIONS: ABSI was significantly associated with CAVI and the presence of MetS in the middle-aged population and helped to discriminate individuals with MetS and increased CAVI. ABSI could serve to identify individuals with MetS and increased arterial stiffness.
Authors: Monika Starzak; Agata Stanek; Grzegorz K Jakubiak; Armand Cholewka; Grzegorz Cieślar Journal: Int J Environ Res Public Health Date: 2022-08-19 Impact factor: 4.614