Literature DB >> 34855086

Measurement of Immunological Parameters to Assess Human Body Readiness for Physical Load.

M A Myagkova1, E A Orlova1, S N Petrochenko2, Z V Bobrova1, S O Bachurin1.   

Abstract

We measured the level of natural antibodies (nAb) to glutamate and GABA reflecting the balance of excitation and inhibition systems and involved in the adaptation processes in athletes receiving normalized physical activity in the dynamics of training (figure skaters, football players, and people actively involved in sports). It was found that each subject has an individual immunological profile and its parameters change in accordance with the training load. The measured levels of nAbs to GABA and glutamate correlate the physical activity of a person. The surveyed football players were divided into 3 groups according to the results of the analysis. Subjects of the first group had reliably high immunological indices in comparison with the control and were at the peak of physical form; in the third group, low immunological indices relative to the control indicated exhaustion and fatigue. The indicators of the second group corresponded to normal and demonstrated the resource of adaptation to load. The developed method can be used for assessing person's readiness for physical activity.
© 2021. Springer Science+Business Media, LLC, part of Springer Nature.

Entities:  

Keywords:  GABA and glutamate; endogenous bioregulators; natural antibodies; physical activity; training load

Mesh:

Substances:

Year:  2021        PMID: 34855086     DOI: 10.1007/s10517-021-05366-2

Source DB:  PubMed          Journal:  Bull Exp Biol Med        ISSN: 0007-4888            Impact factor:   0.804


  8 in total

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Journal:  Eur J Pharmacol       Date:  2016-05-07       Impact factor: 4.432

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Authors:  F P Varodayan; M A Minnig; M Q Steinman; C S Oleata; M W Riley; V Sabino; M Roberto
Journal:  Neuropharmacology       Date:  2019-08-30       Impact factor: 5.250

3.  Glutamate/GABA co-release selectively influences postsynaptic glutamate receptors in mouse cortical neurons.

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Journal:  Neuropharmacology       Date:  2019-08-07       Impact factor: 5.250

4.  Fatty acid biosynthesis from glutamate and glutamine is specifically induced in neuronal cells under hypoxia.

Authors:  Stephen A Brose; Amanda L Marquardt; Mikhail Y Golovko
Journal:  J Neurochem       Date:  2013-12-17       Impact factor: 5.372

Review 5.  A cross-disorder connectome landscape of brain dysconnectivity.

Authors:  Martijn P van den Heuvel; Olaf Sporns
Journal:  Nat Rev Neurosci       Date:  2019-07       Impact factor: 34.870

Review 6.  A systematic review of MRI studies examining the relationship between physical fitness and activity and the white matter of the ageing brain.

Authors:  Claire E Sexton; Jill F Betts; Naiara Demnitz; Helen Dawes; Klaus P Ebmeier; Heidi Johansen-Berg
Journal:  Neuroimage       Date:  2015-10-16       Impact factor: 6.556

Review 7.  Wearable sensors for monitoring the physiological and biochemical profile of the athlete.

Authors:  Dhruv R Seshadri; Ryan T Li; James E Voos; James R Rowbottom; Celeste M Alfes; Christian A Zorman; Colin K Drummond
Journal:  NPJ Digit Med       Date:  2019-07-22

8.  The molecular mechanism underlying GABAergic dysfunction in nucleus accumbens of depression-like behaviours in mice.

Authors:  Ke Ma; Hongxiu Zhang; Shiyuan Wang; Huaxin Wang; Yuan Wang; Juhai Liu; Xiaobin Song; Zhenfei Dong; Xiaochun Han; Yanan Zhang; Honglei Li; Abdul Rahaman; Shijun Wang; Zulqarnain Baloch
Journal:  J Cell Mol Med       Date:  2019-08-20       Impact factor: 5.310

  8 in total

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