Literature DB >> 34855045

Therapeutic potential of marine peptides in cervical and ovarian cancers.

Salman Ahmed1, Haroon Khan2, Sajad Fakhri3, Michael Aschner4, Wai San Cheang5.   

Abstract

Cervical and ovarian cancers contribute significantly to female morbidity and mortality worldwide. The current standard of treatment, including surgical removal, radiation therapy, and chemotherapy, offers poor outcomes. There are many side effects to traditional chemotherapeutic agents and treatment-resistant types, and often the immune response is depressed. As a result, traditional approaches have evolved to include new alternative remedies, such as natural compounds. Aquatic species provide a rich supply of possible drugs. The potential anti-cancer peptides are less toxic to normal cells and can attenuate multiple drug resistance by providing an efficacious treatment approach. The physiological effects of marine peptides are described in this review focusing on various pathways, such as apoptosis, microtubule balance disturbances, suppression of angiogenesis, cell migration/invasion, and cell viability. The review also highlights the potential role of marine peptides as safe and efficacious therapeutic agent for the treatment of cervical and ovarian cancers.
© 2021. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.

Entities:  

Keywords:  Angiogenesis; Apoptosis; Cell cycle arrest; Marine peptides; Metastasis; Mitosis

Mesh:

Substances:

Year:  2021        PMID: 34855045     DOI: 10.1007/s11010-021-04306-y

Source DB:  PubMed          Journal:  Mol Cell Biochem        ISSN: 0300-8177            Impact factor:   3.396


  103 in total

Review 1.  Natural products to prevent drug resistance in cancer chemotherapy: a review.

Authors:  Renyikun Yuan; Ying Hou; Wen Sun; Jie Yu; Xin Liu; Yanan Niu; Jin-Jian Lu; Xiuping Chen
Journal:  Ann N Y Acad Sci       Date:  2017-08       Impact factor: 5.691

Review 2.  Cervical cancer.

Authors:  Paul A Cohen; Anjua Jhingran; Ana Oaknin; Lynette Denny
Journal:  Lancet       Date:  2019-01-12       Impact factor: 79.321

3.  Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries.

Authors:  Hyuna Sung; Jacques Ferlay; Rebecca L Siegel; Mathieu Laversanne; Isabelle Soerjomataram; Ahmedin Jemal; Freddie Bray
Journal:  CA Cancer J Clin       Date:  2021-02-04       Impact factor: 508.702

Review 4.  Novel chemotherapy approaches for cervical cancer.

Authors:  Sujana Movva; Lorna Rodriguez; Hugo Arias-Pulido; Claire Verschraegen
Journal:  Cancer       Date:  2009-07-15       Impact factor: 6.860

5.  Epidemiology of ovarian cancer: a review.

Authors:  Brett M Reid; Jennifer B Permuth; Thomas A Sellers
Journal:  Cancer Biol Med       Date:  2017-02       Impact factor: 4.248

Review 6.  Anticancer peptide: Physicochemical property, functional aspect and trend in clinical application (Review).

Authors:  Wararat Chiangjong; Somchai Chutipongtanate; Suradej Hongeng
Journal:  Int J Oncol       Date:  2020-07-10       Impact factor: 5.650

Review 7.  Novel Therapeutic Strategies for Ovarian Cancer Stem Cells.

Authors:  Nastassja Terraneo; Francis Jacob; Anna Dubrovska; Jürgen Grünberg
Journal:  Front Oncol       Date:  2020-03-17       Impact factor: 6.244

8.  Drug resistance and combating drug resistance in cancer.

Authors:  Xuan Wang; Haiyun Zhang; Xiaozhuo Chen
Journal:  Cancer Drug Resist       Date:  2019-06-19

Review 9.  Marine Natural Products: Promising Candidates in the Modulation of Gut-Brain Axis towards Neuroprotection.

Authors:  Sajad Fakhri; Akram Yarmohammadi; Mostafa Yarmohammadi; Mohammad Hosein Farzaei; Javier Echeverria
Journal:  Mar Drugs       Date:  2021-03-19       Impact factor: 5.118

10.  Estimating the global cancer incidence and mortality in 2018: GLOBOCAN sources and methods.

Authors:  J Ferlay; M Colombet; I Soerjomataram; C Mathers; D M Parkin; M Piñeros; A Znaor; F Bray
Journal:  Int J Cancer       Date:  2018-12-06       Impact factor: 7.396

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  1 in total

1.  Wentilactone A Reverses the NF-κB/ECM1 Signaling-Induced Cisplatin Resistance through Inhibition of IKK/IκB in Ovarian Cancer Cells.

Authors:  Cuiting Lv; Chunxia Ren; Yinjue Yu; Huijing Yin; Caiguo Huang; Gong Yang; Yang Hong
Journal:  Nutrients       Date:  2022-09-14       Impact factor: 6.706

  1 in total

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