Literature DB >> 3485422

Macular infarction after endophthalmitis treated with vitrectomy and intravitreal gentamicin.

B P Conway, P A Campochiaro.   

Abstract

We encountered two cases of macular infarction that occurred after vitrectomy performed for mild endophthalmitis, which, on culture, yielded Staphylococcus epidermidis. At the end of each vitrectomy, 0.4 mg of gentamicin, 1.0 mg of cefazolin, and 0.32 mg of dexamethasone were injected into the vitreous cavity. We are concerned that the macular lesion was a retinal toxic effect of gentamicin because of the recent description of similar lesions occurring after the inadvertent intraocular injection of massive doses of this drug.

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Year:  1986        PMID: 3485422     DOI: 10.1001/archopht.1986.01050150067028

Source DB:  PubMed          Journal:  Arch Ophthalmol        ISSN: 0003-9950


  22 in total

1.  Biocompatibility of pooled human immunoglobulin (Gamunex 10%™) with ocular infusion solutions (BSS™ and BSS Plus™): an in vitro evaluation of a potential antitoxin treatment for infectious endophthalmitis.

Authors:  Dennis P Han; William J O'Brien; Brian Higgins
Journal:  J Ocul Pharmacol Ther       Date:  2011-06-01       Impact factor: 2.671

2.  Intravitreal antibiotic therapy with vancomycin and aminoglycoside: examination of the retinal toxicity of repetitive injections after vitreous and lens surgery.

Authors:  B S Oum; D J D'Amico; H W Kwak; K W Wong
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  1992       Impact factor: 3.117

3.  Fleroxacin pharmacokinetics in aqueous and vitreous humors determined by using complete concentration-time data from individual rabbits.

Authors:  M H Miller; A Madu; G Samathanam; D Rush; C N Madu; K Mathisson; M Mayers
Journal:  Antimicrob Agents Chemother       Date:  1992-01       Impact factor: 5.191

4.  Metastatic Staphylococcus aureus endophthalmitis: a case report.

Authors:  C J O'Brien; G M Kyle
Journal:  Br J Ophthalmol       Date:  1988-03       Impact factor: 4.638

Review 5.  Common ocular infections. A prescriber's guide.

Authors:  S P Donahue; J M Khoury; R P Kowalski
Journal:  Drugs       Date:  1996-10       Impact factor: 9.546

Review 6.  Bacillus cereus endophthalmitis.

Authors:  D B David; G R Kirkby; B A Noble
Journal:  Br J Ophthalmol       Date:  1994-07       Impact factor: 4.638

Review 7.  Factors affecting the efficacy of antibiotics in the treatment of experimental postoperative endophthalmitis.

Authors:  G A Stern
Journal:  Trans Am Ophthalmol Soc       Date:  1993

Review 8.  Modeling intraocular bacterial infections.

Authors:  Roger A Astley; Phillip S Coburn; Salai Madhumathi Parkunan; Michelle C Callegan
Journal:  Prog Retin Eye Res       Date:  2016-05-03       Impact factor: 21.198

9.  Antimicrobial pharmacokinetics in endophthalmitis treatment: studies of ceftazidime.

Authors:  T A Meredith
Journal:  Trans Am Ophthalmol Soc       Date:  1993

10.  Postoperative conjunctival chemosis in cataract surgery caused by subconjunctival gentamicin injection.

Authors:  M Pande
Journal:  Br J Ophthalmol       Date:  1991-11       Impact factor: 4.638

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