Literature DB >> 34851451

Endoscopic transcanal attico-antrostomy versus endoscopic-assisted canal wall up mastoidectomy in management of localized cholesteatoma: a randomized clinical trial.

Waleed Moneir1, Ahmed Hemdan1, Noha Ahmed El-Kholy2, Mohamed El-Kotb1, Mohamed El-Okda1.   

Abstract

OBJECTIVES: This study aims to compare results of endoscopic transcanal tympanoplasty with attico-antrostomy with endoscopic-assisted canal wall up mastoidectomy in treatment of cases of limited attic cholesteatoma.
MATERIALS AND METHODS: A prospective randomized single-blinded study involving 40 patients with limited attic cholesteatoma was conducted. Randomization of the patients into two groups was done; 20 patients are managed by endoscopic transcanal tympanoplasty with attico-antrostomy, while the other 20 patients are managed by endoscopic-assisted canal wall up mastoidectomy. Primary outcome is recidivism, while secondary outcomes include hearing results, operative time, pain score and associated complications.
RESULTS: Comparable recidivism rate was found in the two groups. The endoscopic-assisted canal wall up mastoidectomy group was associated with significantly longer duration of surgery and higher postoperative pain score. There was no significant difference between both the groups regarding hearing results and associated complications.
CONCLUSION: In localized attic cholesteatoma cases, endoscopic transcanal tympanoplasty with attico-antrostomy is a time-saving less-invasive reliable technique with good eradication results. CLINICAL TRIAL REGISTRY: ClinicalTrials.gov (NCT04959539) "retrospectively registered" at 12/7/2021.
© 2021. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.

Entities:  

Keywords:  Cholesteatoma; Endoscopic attico-antrostomy; Mastoidectomy; Recidivism

Mesh:

Year:  2021        PMID: 34851451     DOI: 10.1007/s00405-021-07200-x

Source DB:  PubMed          Journal:  Eur Arch Otorhinolaryngol        ISSN: 0937-4477            Impact factor:   3.236


  2 in total

Review 1.  Molecular biology of cholesteatoma.

Authors:  Alma Maniu; Oana Harabagiu; Maria Perde Schrepler; Andreea Cătană; Bogdan Fănuţă; Carmen Aurelia Mogoantă
Journal:  Rom J Morphol Embryol       Date:  2014       Impact factor: 1.033

Review 2.  Results of endoscopic middle ear surgery for cholesteatoma treatment: a systematic review.

Authors:  L Presutti; F M Gioacchini; M Alicandri-Ciufelli; D Villari; D Marchioni
Journal:  Acta Otorhinolaryngol Ital       Date:  2014-06       Impact factor: 2.124

  2 in total
  1 in total

1.  Clinical Analysis of 85 Cases of External Auditory Canal Cholesteatoma Surgery under Specialized Endoscopy.

Authors:  Yanan Guo; Minfei Qian; Jiping Li; Ji Xu; Hao Chen; Hua Zhang
Journal:  Biomed Res Int       Date:  2022-10-05       Impact factor: 3.246

  1 in total

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