Literature DB >> 34850623

Report and Abstracts of the 18th Meeting of the Interuniversity Institute of Myology: Virtual meeting, October 21-24, 2021.

Francesca Grassi1, Sestina Falcone2.   

Abstract

In 2021, as the situation due to COVID-19 pandemic was still uncertain, the 18 th annual meeting of the Interuniversity Institute of Myology (IIM), took place on a virtual platform, following the same organization already tested for the previous edition. Participants from Italy, European countries, Canada and USA included clinicians, scientists, pharmaceutical companies and representatives of patient organizations. Four keynote speakers presented new insights into the modulation of muscle stem cell self-renewal in the treatment of neuromuscular disease, the role of nuclear positioning in muscle function, regeneration and tumorigenesis in the heart and advances on therapies of muscular dystrophies. Young PhD students and trainees presented oral communications distributed in five scientific sessions and posters in two poster sessions. On October 21, 2021, selected young scientists participated in the "High Training Course on Advanced Myology", organized with the University of Perugia, Italy. This course consisted of lectures on muscle regeneration and therapeutic perspectives by internationally recognized speakers, followed by roundtable discussions on "Omics technologies in myology" and "New therapeutic approaches", plus the meeting itself. Young trainees, winners of past IIM conferences, forming the Young IIM Committee, selected one of Keynote speakers and were involved in the organization of scientific sessions and roundtable discussions. The friendly welcoming of the meeting, which has strongly characterized this event and is of great help in facilitating scientific exchanges and stimulating novel collaborations, was the hallmark of the conference this year again, even on virtual platform. Breakthrough studies showing interdisciplinary works are fostering new avenues in the field of myology. This year again, scientists and students attended the meeting at the huger number, challenging the difficulties due to the COVID-19 pandemic. All participants shared the wish to continue and implement IIM meeting with new insights on muscle biology, perspectives in the understanding of the muscle-related diseases and in novel therapeutic approaches. We report here abstracts of the meeting describing basic, translational, and clinical research contributing to the large field of myology.

Entities:  

Year:  2021        PMID: 34850623      PMCID: PMC8758965          DOI: 10.4081/ejtm.2021.10270

Source DB:  PubMed          Journal:  Eur J Transl Myol        ISSN: 2037-7452


  16 in total

Review 1.  Comprehensive Overview of Non-coding RNAs in Cardiac Development.

Authors:  Enrico Pozzo; Yoke Chin Chai; Maurilio Sampaolesi
Journal:  Adv Exp Med Biol       Date:  2020       Impact factor: 2.622

Review 2.  Sarcopenia: Aging-Related Loss of Muscle Mass and Function.

Authors:  Lars Larsson; Hans Degens; Meishan Li; Leonardo Salviati; Young Il Lee; Wesley Thompson; James L Kirkland; Marco Sandri
Journal:  Physiol Rev       Date:  2019-01-01       Impact factor: 37.312

3.  Intermittent glucocorticoid steroid dosing enhances muscle repair without eliciting muscle atrophy.

Authors:  Mattia Quattrocelli; David Y Barefield; James L Warner; Andy H Vo; Michele Hadhazy; Judy U Earley; Alexis R Demonbreun; Elizabeth M McNally
Journal:  J Clin Invest       Date:  2017-05-08       Impact factor: 14.808

4.  Pulsed glucocorticoids enhance dystrophic muscle performance through epigenetic-metabolic reprogramming.

Authors:  Mattia Quattrocelli; Aaron S Zelikovich; Zhen Jiang; Clara Bien Peek; Alexis R Demonbreun; Nancy L Kuntz; Grant D Barish; Saptarsi M Haldar; Joseph Bass; Elizabeth M McNally
Journal:  JCI Insight       Date:  2019-12-19

Review 5.  Osteosarcopenia: where osteoporosis and sarcopenia collide.

Authors:  Michael A Clynes; Celia L Gregson; Olivier Bruyère; Cyrus Cooper; Elaine M Dennison
Journal:  Rheumatology (Oxford)       Date:  2021-02-01       Impact factor: 7.580

6.  Reversible reprogramming of cardiomyocytes to a fetal state drives heart regeneration in mice.

Authors:  Yanpu Chen; Felipe F Lüttmann; Eric Schoger; Hans R Schöler; Laura C Zelarayán; Kee-Pyo Kim; Jody J Haigh; Johnny Kim; Thomas Braun
Journal:  Science       Date:  2021-09-23       Impact factor: 47.728

7.  Intraperitoneal injection of microencapsulated Sertoli cells restores muscle morphology and performance in dystrophic mice.

Authors:  Sara Chiappalupi; Giovanni Luca; Francesca Mancuso; Luca Madaro; Francesca Fallarino; Carmine Nicoletti; Mario Calvitti; Iva Arato; Giulia Falabella; Laura Salvadori; Antonio Di Meo; Antonello Bufalari; Stefano Giovagnoli; Riccardo Calafiore; Rosario Donato; Guglielmo Sorci
Journal:  Biomaterials       Date:  2015-10-23       Impact factor: 12.479

Review 8.  Therapeutic application of Sertoli cells for treatment of various diseases.

Authors:  Rachel L Washburn; Taylor Hibler; Lea Ann Thompson; Gurvinder Kaur; Jannette M Dufour
Journal:  Semin Cell Dev Biol       Date:  2021-04-25       Impact factor: 7.727

9.  Acetylation of PAX7 controls muscle stem cell self-renewal and differentiation potential in mice.

Authors:  Marie-Claude Sincennes; Caroline E Brun; Alexander Y T Lin; Tabitha Rosembert; David Datzkiw; John Saber; Hong Ming; Yoh-Ichi Kawabe; Michael A Rudnicki
Journal:  Nat Commun       Date:  2021-05-31       Impact factor: 14.919

10.  Valproic acid stimulates myogenesis in pluripotent stem cell-derived mesodermal progenitors in a NOTCH-dependent manner.

Authors:  Natacha Breuls; Nefele Giarratana; Laura Yedigaryan; Gabriel Miró Garrido; Paolo Carai; Stephane Heymans; Adrian Ranga; Christophe Deroose; Maurilio Sampaolesi
Journal:  Cell Death Dis       Date:  2021-07-05       Impact factor: 8.469

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