Literature DB >> 3484631

Demonstration of anaphylatoxins C3a, C4a and C5a in the scales of psoriasis and inflammatory pustular dermatoses.

H Takematsu, K Ohkohchi, H Tagami.   

Abstract

Complement components C3a, C4a and C5a were assayed in corneal scale extracts from psoriasis and other dermatoses characterized by sterile subcorneal pustules, using radioimmunoassay. Larger amounts were detected in psoriasis and related pustular dermatoses than in extracts of non-inflammatory stratum corneum. It is concluded that complement is activated via the classical pathway and releases the neutrophil chemotactic fragment C5a.

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Year:  1986        PMID: 3484631     DOI: 10.1111/j.1365-2133.1986.tb02773.x

Source DB:  PubMed          Journal:  Br J Dermatol        ISSN: 0007-0963            Impact factor:   9.302


  14 in total

1.  Soluble interleukin-2 receptors and psoriasis.

Authors:  R Dummer; F G Dunkel
Journal:  Arch Dermatol Res       Date:  1991       Impact factor: 3.017

2.  Activation of the complement system generates antibacterial peptides.

Authors:  Emma Andersson Nordahl; Victoria Rydengård; Patrik Nyberg; D Patric Nitsche; Matthias Mörgelin; Martin Malmsten; Lars Björck; Artur Schmidtchen
Journal:  Proc Natl Acad Sci U S A       Date:  2004-11-18       Impact factor: 11.205

3.  Leukocyte chemotactic properties of soluble horny contents in epidermal cysts.

Authors:  H Takematsu; T Terui; W Torinuki; H Tagami
Journal:  Arch Dermatol Res       Date:  1987       Impact factor: 3.017

4.  Effects of psoriatic scale extracts on oxidative metabolic responses in granulocytes assessed by chemiluminescence.

Authors:  T Kato; T Terui; H Takematsu; H Tagami
Journal:  Inflammation       Date:  1989-02       Impact factor: 4.092

5.  Psoriatic skin lesions contain a novel lipid neutrophil chemokinetic compound which is distinct from known chemoattractant eicosanoids.

Authors:  R D Camp; F M Cunningham; N J Fincham; M W Greaves; A Kobza Black; A I Mallet; P M Woollard
Journal:  Br J Pharmacol       Date:  1988-08       Impact factor: 8.739

6.  Demonstration of neutrophil chemotactic anaphylatoxins in human dandruff.

Authors:  T Kikuchi; I Horii; T Sakamoto; Y Nakayama; H Tagami
Journal:  Arch Dermatol Res       Date:  1989       Impact factor: 3.017

7.  Human monocyte-derived dendritic cells are chemoattracted to C3a after up-regulation of the C3a receptor with interferons.

Authors:  Ralf Gutzmer; Margarete Lisewski; Jörg Zwirner; Susanne Mommert; Carola Diesel; Miriam Wittmann; Alexander Kapp; Thomas Werfel
Journal:  Immunology       Date:  2004-04       Impact factor: 7.397

Review 8.  The role of complement-derived mediators in inflammatory skin diseases.

Authors:  H Tagami
Journal:  Arch Dermatol Res       Date:  1992       Impact factor: 3.017

9.  Complement modulates the cutaneous microbiome and inflammatory milieu.

Authors:  Christel Chehoud; Stavros Rafail; Amanda S Tyldsley; John T Seykora; John D Lambris; Elizabeth A Grice
Journal:  Proc Natl Acad Sci U S A       Date:  2013-08-26       Impact factor: 11.205

10.  Surprisingly high levels of anaphylatoxin C5a des Arg are extractable from psoriatic scales.

Authors:  K Bergh; O J Iversen; H Lysvand
Journal:  Arch Dermatol Res       Date:  1993       Impact factor: 3.017

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