Literature DB >> 3484624

Effect of transfusion on immune function in a traumatized animal model.

J P Waymack, J Rapien, D Garnett, J S Tweddell, J W Alexander.   

Abstract

Blood transfusions repeatedly have been shown to prolong allograft survival, probably by stimulating suppressor T lymphocytes. The effects of transfusions on immune function in traumatized patients has not previously been investigated. We investigated the effects of transfusions on the immune system using a burned rat model. The transfusions were found to have no effect on the white blood cell counts, differential cell count, or neutrophil migration and bactericidal index. Those animals that received transfusion did exhibit impaired cell-mediated immunity and macrophage migration. Blood transfusions seem to increase further the immunosuppression seen with trauma and surgery.

Entities:  

Mesh：

Year:  1986        PMID： 3484624     DOI： 10.1001/archsurg.1986.01400010056007

Source DB:  PubMed          Journal:  Arch Surg        ISSN： 0004-0010


  10 in total

1.  Blood transfusion impairs the healing of experimental intestinal anastomoses.

Authors:  T Tadros; T Wobbes; T Hendriks
Journal:  Ann Surg       Date:  1992-03       Impact factor: 12.969

2.  Factors affecting morbidity following hepatic trauma. A prospective analysis of 482 injuries.

Authors:  T C Fabian; M A Croce; G G Stanford; L W Payne; E C Mangiante; G R Voeller; K A Kudsk
Journal:  Ann Surg       Date:  1991-06       Impact factor: 12.969

3.  Effect of blood transfusions on macrophage-lymphocyte interaction in an animal model.

Authors:  J P Waymack; K Balakrishnan; N McNeal; S Gonce; P Miskell; G D Warden; J W Alexander
Journal:  Ann Surg       Date:  1986-12       Impact factor: 12.969

4.  Effect of varying number and volume of transfusions on mortality rate following septic challenge in an animal model.

Authors:  J P Waymack; G D Warden; P Miskell; S Gonce; J W Alexander
Journal:  World J Surg       Date:  1987-06       Impact factor: 3.352

5.  Anastomotic leakage contributes to the risk for systemic recurrence in stage II colorectal cancer.

Authors:  Hiroshi Katoh; Keishi Yamashita; Guoqin Wang; Takeo Sato; Takatoshi Nakamura; Masahiko Watanabe
Journal:  J Gastrointest Surg       Date:  2010-11-18       Impact factor: 3.452

6.  Enteral nutrition during multimodality therapy in upper gastrointestinal cancer patients.

Authors:  J M Daly; F N Weintraub; J Shou; E F Rosato; M Lucia
Journal:  Ann Surg       Date:  1995-04       Impact factor: 12.969

7.  Immune and metabolic effects of arginine in the surgical patient.

Authors:  J M Daly; J Reynolds; A Thom; L Kinsley; M Dietrick-Gallagher; J Shou; B Ruggieri
Journal:  Ann Surg       Date:  1988-10       Impact factor: 12.969

8.  Arginine-supplemented diets improve survival in gut-derived sepsis and peritonitis by modulating bacterial clearance. The role of nitric oxide.

Authors:  L Gianotti; J W Alexander; T Pyles; R Fukushima
Journal:  Ann Surg       Date:  1993-06       Impact factor: 12.969

9.  A comparison of autologous and homologous transfusions in spinal fusion.

Authors:  Moon-Soo Park; Seong-Hwan Moon; Hak-Sun Kim; Soo-Bong Hahn; Hui-Wan Park; Si-Young Park; Hwan-Mo Lee
Journal:  Yonsei Med J       Date:  2006-12-31       Impact factor: 2.759

10.  Metabolomics Approach Based on Multivariate Techniques for Blood Transfusion Reactions.

Authors:  Seul Ji Lee; Haiping Wang; Soo Hyun Ahn; Mi Kwon Son; Gyu Hwan Hyun; Sang Jun Yoon; Jeongmi Lee; Jeong Hill Park; Johan Lim; Soon-Sun Hong; Sung Won Kwon
Journal:  Sci Rep       Date:  2019-02-11       Impact factor: 4.379
  10 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.