Literature DB >> 34845202

Squamous cell carcinoma of the renal pelvis in a patient with long-term spinal cord injury-a case report.

Oliver Balzer1, Ralf Böthig2, Wolfgang Schöps3, Roland Thietje4, Armin Soave5, Thura Kadhum6, Klaus Golka7.   

Abstract

INTRODUCTION: For individuals with spinal cord injury/disease (SCI/D) the risk of developing a stone in the upper urinary tract is up to six times higher than in the able-bodied population. Upper urinary tract carcinomas, in general, are rare and account for only 5-10% of all urinary tract carcinomas. It is believed that chronic upper urinary tract irritation caused by e.g., kidney stones or recurrent upper urinary tract infections may be associated with an increased risk of renal squamous cell carcinoma (RSCC). CASE
PRESENTATION: We report on a 64-year-old male who suffered a spinal cord injury in 1981 resulting in a complete sensory and motor impairment below T6, AIS A. Recurrent left-sided kidney stone disease had to be treated repeatedly from 1984 onwards. Despite repeated surgical attempts, it was ultimately not possible to achieve stone clearance in the long term. Within the concept of life-long surveillance of SCI/D, the patient was examined regularly, including ultrasound examinations of the kidneys. Six months after the last control examination, the patient was admitted to our hospital with a locally advanced tumor of the left kidney, so that only the option of palliative treatment remained. Histologically an RSCC was found. DISCUSSION: As people with SCI/D have a higher risk of developing kidney stones, it is of utmost importance to check regularly for stone disease and, if necessary, treat with the aim of long-term stone clearance in order to protect renal function and to avert potentially malignant changes at an early stage.
© 2021. The Author(s), under exclusive licence to International Spinal Cord Society.

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Year:  2021        PMID: 34845202      PMCID: PMC8630007          DOI: 10.1038/s41394-021-00466-7

Source DB:  PubMed          Journal:  Spinal Cord Ser Cases        ISSN: 2058-6124


  17 in total

1.  Outcomes of renal calculi in patients with spinal cord injury.

Authors:  Giulia I Lane; William W Roberts; Rachel Mann; Diana O'Dell; John T Stoffel; J Quentin Clemens; Anne P Cameron
Journal:  Neurourol Urodyn       Date:  2019-07-11       Impact factor: 2.696

2.  Urothelial and Squamous Cell Carcinoma of Renal Pelvis - A Rare Case Report.

Authors:  Surekha B Hippargi; Savitri Mallikarjun Nerune; Mayank Kumar
Journal:  J Clin Diagn Res       Date:  2016-09-01

Review 3.  Systematic review of bladder cancer outcomes in patients with spina bifida.

Authors:  K O Rove; D A Husmann; D T Wilcox; G J Vricella; T T Higuchi
Journal:  J Pediatr Urol       Date:  2017-06-01       Impact factor: 1.830

Review 4.  Renal stone disease in spinal-cord-injured patients.

Authors:  Blayne Welk; Andrew Fuller; Hassan Razvi; John Denstedt
Journal:  J Endourol       Date:  2012-04-17       Impact factor: 2.942

5.  The surgical management of upper tract stone disease among spinal cord-injured patients.

Authors:  B Welk; S Shariff; M Ordon; B Catharine Craven; S Herschorn; A X Garg
Journal:  Spinal Cord       Date:  2013-03-12       Impact factor: 2.772

6.  Prevalence, management, and prognosis of bladder cancer in patients with neurogenic bladder: A systematic review.

Authors:  Salima Ismail; Gilles Karsenty; Emmanuel Chartier-Kastler; Olivier Cussenot; Eva Compérat; Morgan Rouprêt; Véronique Phé
Journal:  Neurourol Urodyn       Date:  2017-11-23       Impact factor: 2.696

7.  High-grade urothelial carcinoma of the renal pelvis: clinicopathologic study of 108 cases with emphasis on unusual morphologic variants.

Authors:  Delia Perez-Montiel; Paul E Wakely; Ondrej Hes; Michal Michal; Saul Suster
Journal:  Mod Pathol       Date:  2006-04       Impact factor: 7.842

8.  Urinary tract infections and risk of squamous cell carcinoma bladder cancer: A Danish nationwide case-control study.

Authors:  Anton Pottegård; Kasper B Kristensen; Søren Friis; Jesper Hallas; Jørgen B Jensen; Mette Nørgaard
Journal:  Int J Cancer       Date:  2020-01-08       Impact factor: 7.396

9.  Traumatic spinal cord injury confers bladder cancer risk to patients managed without permanent urinary catheterization: lessons from a comparison of clinical data with the national database.

Authors:  Ralf Böthig; Christian Tiburtius; Kai Fiebag; Birgitt Kowald; Sven Hirschfeld; Roland Thietje; Ines Kurze; Wolfgang Schöps; Holger Böhme; Albert Kaufmann; Michael Zellner; Thura Kadhum; Klaus Golka
Journal:  World J Urol       Date:  2020-01-13       Impact factor: 4.226

10.  Incidentally detected squamous cell carcinoma of renal pelvis in patients with staghorn calculi: case series with review of the literature.

Authors:  Ayushi Jain; Deepti Mittal; Arpita Jindal; Ranjana Solanki; Suman Khatri; Archana Parikh; Kamlesh Yadav
Journal:  ISRN Oncol       Date:  2011-04-26
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