Literature DB >> 34844215

Ischemic Stroke in a Child after a Probable Scorpion Sting.

Laura Naranjo1, Fernando Carrillo-Villaseñor2, Gina D'Suze3, Carlos Sevcik3, Nathan Gundacker4, Amy Rao5, Carlos Franco-Paredes5,6, José Antonio Suárez7.   

Abstract

Scorpion stings are common emergencies in the tropics. Species-specific antivenom therapies are available. However, fatalities resulting from scorpion stings remain a public health concern in many settings. Children residing in rural towns and peri-urban areas represent the most vulnerable populations. Delays in the diagnosis of scorpion stings often occur as a result of the non-specific clinical presentations, which then lead to life-threatening complications. We report a 2-year-old Venezuelan boy presenting with acute pancreatitis and pulmonary edema without an identifiable cause 48 hours after his initial symptoms. We administered antivenom therapy when an undetected scorpion sting was suspected. Despite some initial clinical improvement with respect to his acute pancreatitis, pulmonary edema, and coagulation abnormalities, our patient experienced an ischemic stroke. Fortunately, our patient did demonstrate some neurological improvement. Although acute pancreatitis and pulmonary edema are known end-organ damage manifestations of the sting of Tityus in the Americas, our particular case illustrates the risk of ischemic stroke.

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Year:  2021        PMID: 34844215      PMCID: PMC8922484          DOI: 10.4269/ajtmh.21-0880

Source DB:  PubMed          Journal:  Am J Trop Med Hyg        ISSN: 0002-9637            Impact factor:   3.707


  11 in total

1.  Modelling Tityus scorpion venom and antivenom pharmacokinetics. Evidence of active immunoglobulin G's F(ab')2 extrusion mechanism from blood to tissues.

Authors:  C Sevcik; G D'Suze; P Díaz; V Salazar; C Hidalgo; H Azpúrua; N Bracho
Journal:  Toxicon       Date:  2004-12-01       Impact factor: 3.033

2.  Ischemic infarction of cerebral cortex in a child with scorpion sting envenomation.

Authors:  Rajniti Prasad; Shipra Suri; Om Prakash Mishra
Journal:  Indian J Pediatr       Date:  2013-04-19       Impact factor: 1.967

3.  Epidemiological and clinical study on scorpionism in French Guiana.

Authors:  Mohamed Benmosbah; Pascal Guegueniat; Claire Mayence; Gerald Egmann; Elenga Narcisse; Stephan Gonon; Didier Hommel; Hatem Kallel
Journal:  Toxicon       Date:  2013-06-19       Impact factor: 3.033

4.  Tityus discrepans scorpion venom activates platelets through GPVI and a novel Src-dependent signaling pathway.

Authors:  Josmary Brazón; Craig E Hughes; Jun Mori; Carlos Sevcik; Gina D'suze; Steve P Watson
Journal:  Platelets       Date:  2011-02-15       Impact factor: 3.862

5.  Epilepsy due to a destructive brain lesion caused by a scorpion sting.

Authors:  Leonardo Bonilha; Fernando Cendes; Enrico Ghizoni; Ronan José Vieira; Li Min Li
Journal:  Arch Neurol       Date:  2004-08

6.  Cerebral atrophy and subdural haemorrhage after cerebellar and cerebral infarcts in an 8-month-old child after having been stung by a scorpion.

Authors:  Ahmet Sığırcı; Mehmet Öztürk; Cengiz Yakıncı
Journal:  BMJ Case Rep       Date:  2014-06-24

7.  Antigenic cross-reactivity between sixteen venoms from scorpions belonging to six genera.

Authors:  G D'Suze; S Moncada; C González; C Sevcik; A Alagón
Journal:  Clin Toxicol (Phila)       Date:  2007       Impact factor: 4.467

8.  Relationship between plasmatic levels of various cytokines, tumour necrosis factor, enzymes, glucose and venom concentration following Tityus scorpion sting.

Authors:  G D'Suze; S Moncada; C González; C Sevcik; V Aguilar; A Alagón
Journal:  Toxicon       Date:  2003-03-01       Impact factor: 3.033

9.  Sympathetic nervous system activation, antivenin administration and cardiovascular manifestations of scorpion envenomation.

Authors:  Carmen A Mazzei de Dàvila; Diego F Dàvila; Jose H Donis; Gabriela Arata de Bellabarba; Vanesa Villarreal; Juan S Barboza
Journal:  Toxicon       Date:  2002-09       Impact factor: 3.033

10.  Motor aphasia: A rare complication of scorpion sting.

Authors:  Vinayak Y Kshirsagar; Minhajuddin Ahmed; Sylvia M Colaco
Journal:  J Pediatr Neurosci       Date:  2012-09
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