| Literature DB >> 34843816 |
Mary Shamya Arokiarajan1, Rajasekar Thirunavukkarasu2, Jerrine Joseph1, Obluchinskaya Ekaterina3, Wilson Aruni1.
Abstract
Marine ecosystem associated organisms are an affluent source of bioactive compounds. Polysaccharides with unique structural and practical entities have gained special studies interest inside the current biomedical zone. Polysaccharides are the main components of marine algae, plants, animals, insects, and microorganisms. In recent times research on seaweed is more persistent for extraction of natural bioactive "Sulfated polysaccharides" (SPs). The considerable amount of SP exists in the algae in the form of fucans, fucoidans, carrageenans, ulvan, etc. Major function of SPs is to act as a defensive lattice towards the infective organism. All SPs possess the high potential and possess a broad range of therapeutic applications as antitumor, immunomodulatory, vaccine adjuvant, anti-inflammatory, anticoagulant, antiviral, antiprotozoal, antimicrobial, antilipemic, therapy of regenerative medicine, also in drug delivery and tissue engineering application. This review aims to discuss the biomedicine applications of sulfated polysaccharides from marine seaweeds.Entities:
Keywords: Antitumor; Immunomodulatory; Nontoxicity emphasize; Seaweed; Sulfated polysaccharide; Vaccine adjuvant
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Year: 2021 PMID: 34843816 DOI: 10.1016/j.ijbiomac.2021.11.142
Source DB: PubMed Journal: Int J Biol Macromol ISSN: 0141-8130 Impact factor: 6.953