Literature DB >> 348237

Microviscosity changes during differentiation of neuroblastoma cells.

S W de Laat, P T van der Saag, S A Nelemans, M Shinitzky.   

Abstract

Microviscosity (eta) of the plasma-membrane lipid matrix was measured in exponentially growing and differentiating C1300 mouse neuroblastoma cells, attached to a glass substratum, by fluorescence polarisation of 1,6-diphenyl-1,3,5-hexatriene. Upon differentiation eta decreases progressively, reaching values below those observed in the growth phase. Treatment of the cells with dipalmitoyl phosphatidylcholine vesicles reversibly inhibits morphological differentiation. The results show that a high membrane fluidity is a prerequisite for differentiation.

Entities:  

Mesh：

Year:  1978        PMID： 348237     DOI： 10.1016/0005-2736(78)90019-6

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN： 0006-3002


  4 in total

Review 1.  Role of the growth cone in neuronal differentiation.

Authors:  C O Van Hooff; A B Oestreicher; P N De Graan; W H Gispen
Journal:  Mol Neurobiol       Date:  1989 Spring-Summer       Impact factor: 5.590

2.  Differentiated neuroblastoma cells are more susceptible to aluminium toxicity than developing cells.

Authors:  M Roll; E Banin; H Meiri
Journal:  Arch Toxicol       Date:  1989       Impact factor: 5.153

3.  Lateral diffusion of membrane lipids and proteins during the cell cycle of neuroblastoma cells.

Authors:  S W de Laat; P T van der Saag; E L Elson; J Schlessinger
Journal:  Proc Natl Acad Sci U S A       Date:  1980-03       Impact factor: 11.205

4.  Biochemical and cellular aspects of the anticancer activity of selenium.

Authors:  S Y Yu; P Ao; L M Wang; S L Huang; H C Chen; X P Lu; Q Y Liu
Journal:  Biol Trace Elem Res       Date:  1988 Jan-Apr       Impact factor: 3.738
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.