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Literature DB >> 34823006

Anger management: Mechanisms of glutamate receptor-mediated synaptic plasticity underlying animal aggression.

Abstract

Excessive and recurring violent aggression is a serious concern for society and a symptom of many psychiatric diseases. Substance abuse, attack experience, and social and traumatic stress increase vulnerability to developing this type of aggression. Glutamate receptors are an intriguing target for long-term treatment. This review will assess the importance of glutamate receptors and glutamatergic pathways in aggression, focusing on the role of glutamate receptor-mediated synaptic plasticity in experience-dependent long-lasting aggression. By synthesizing what is known about glutamatergic systems in aggression, it is hoped more effective treatments can be developed.

Entities: Chemical

Keywords: Aggression; Experience; Glutamate; Stress; Synaptic plasticity

Mesh：
Aggression

Year: 2021 PMID： 34823006 PMCID： PMC8959042 DOI： 10.1016/j.biocel.2021.106120

Source DB: PubMed Journal: Int J Biochem Cell Biol ISSN： 1357-2725 Impact factor: 5.085

58 in total

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Authors: Koh Shimizu; Natsuki Kurosawa; Kenjiro Seki
Journal: Physiol Behav Date: 2015-11-03

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Authors: Chih-Hua Chang; Po-Wu Gean
Journal: Cell Rep Date: 2019-07-30 Impact factor: 9.423

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Authors: Klaus A Miczek; Sietse F de Boer; Jozsef Haller
Journal: Psychopharmacology (Berl) Date: 2013-02-21 Impact factor: 4.530

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Authors: Jacob C Nordman; Xiaoyu Ma; Qinhua Gu; Michael Potegal; He Li; Alexxai V Kravitz; Zheng Li
Journal: J Neurosci Date: 2020-05-18 Impact factor: 6.167

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Journal: Eur J Pharmacol Date: 2006-09-08 Impact factor: 4.432

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Journal: Drug Alcohol Depend Date: 2003-01-24 Impact factor: 4.492

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Authors: José Francisco Navarro; Vanessa De Castro; Mercedes Martín-López
Journal: Eur J Pharmacol Date: 2008-02-29 Impact factor: 4.432

8. Amantadine: a review of use in child and adolescent psychiatry.

Authors: Sheik Hosenbocus; Raj Chahal
Journal: J Can Acad Child Adolesc Psychiatry Date: 2013-02

9. The effects of memantine on behavioral disturbances in patients with Alzheimer's disease: a meta-analysis.

Authors: Taro Kishi; Shinji Matsunaga; Nakao Iwata
Journal: Neuropsychiatr Dis Treat Date: 2017-07-20 Impact factor: 2.570

Review 10. Glycine Signaling in the Framework of Dopamine-Glutamate Interaction and Postsynaptic Density. Implications for Treatment-Resistant Schizophrenia.

Authors: Andrea de Bartolomeis; Mirko Manchia; Federica Marmo; Licia Vellucci; Felice Iasevoli; Annarita Barone
Journal: Front Psychiatry Date: 2020-05-14 Impact factor: 4.157

3 in total