Literature DB >> 34822004

A real-world accuracy of oral mucositis grading in patients undergoing hematopoietic stem cell transplantation.

Midori Nakagaki1,2, Nicole C Gavin3,4,5, Alexandra Clavarino6, Glen A Kennedy3,4, Karen Whitfield7,8.   

Abstract

PURPOSE: Oral mucositis is a common complication in patients undergoing hematopoietic stem cell transplantation. Accurate oral mucositis grading is essential for both clinical practice and oral mucositis research. This study aimed to evaluate the accuracy of daily oral mucositis grading by nurses in a tertiary hospital in Australia.
METHODS: A retrospective study was undertaken to review the daily patient oral assessment record, including diet, pain, erythema, ulceration and the oral mucositis grade based on World Health Organization (WHO) oral mucositis grading scale. The accuracy of the grade was determined by the observations recorded, and reasons for inaccuracy were documented. Any repetition of the same error in the same patient was noted.
RESULTS: In total, 6841 oral assessments in 373 patients, conducted between 2017 and 2020, were reviewed. A total of 70% (N = 4781) were graded correctly. Of these, 64% (N = 3043) were grade 0. When the grade 0 scores were excluded, the accuracy of grading was reduced to 46% (N = 1738). Common reasons for incorrect grading included: unable to grade due to diet not specified, no ulceration and no pain was scored grade 1, no ulceration was scored as grade 2-4, oral intake was not taken into account, and pain without ulcer was scored 0. A total of 77% of the errors were repeated in the same patient on consecutive days.
CONCLUSIONS: Our results suggest there is frequent inaccurate evaluation of oral mucositis and a need for nurse training to accurately assess oral mucositis.
© 2021. Crown.

Entities:  

Keywords:  Assessment; Hematopoietic stem cell transplantation; Nursing; Oral mucositis

Mesh:

Year:  2021        PMID: 34822004     DOI: 10.1007/s00520-021-06654-3

Source DB:  PubMed          Journal:  Support Care Cancer        ISSN: 0941-4355            Impact factor:   3.603


  14 in total

1.  The 20 item oral mucositis index: reliability and validity in bone marrow and stem cell transplant patients.

Authors:  Deborah B McGuire; Douglas E Peterson; Susan Muller; Donna C Owen; Marina F Slemmons; Mark M Schubert
Journal:  Cancer Invest       Date:  2002       Impact factor: 2.176

Review 2.  Chemotherapy or radiation-induced oral mucositis.

Authors:  Rajesh V Lalla; Deborah P Saunders; Douglas E Peterson
Journal:  Dent Clin North Am       Date:  2014-04

Review 3.  A systematic review of oral assessment instruments: what can we recommend to practitioners in children's and young people's cancer care?

Authors:  Faith Gibson; Elizabeth M Auld; Gemma Bryan; Suzanne Coulson; Jean V Craig; Anne-Marie Glenny
Journal:  Cancer Nurs       Date:  2010 Jul-Aug       Impact factor: 2.592

4.  Reliability and validity of a patient self-administered daily questionnaire to assess impact of oral mucositis (OM) on pain and daily functioning in patients undergoing autologous hematopoietic stem cell transplantation (HSCT).

Authors:  P J Stiff; H Erder; W I Bensinger; C Emmanouilides; T Gentile; J Isitt; Z J Lu; R Spielberger
Journal:  Bone Marrow Transplant       Date:  2006-02       Impact factor: 5.483

5.  Longitudinal evaluation of the oral mucositis weekly questionnaire-head and neck cancer, a patient-reported outcomes questionnaire.

Authors:  Joel B Epstein; Jennifer L Beaumont; Clement K Gwede; Barbara Murphy; Adam S Garden; Ruby Meredith; Quynh-Thu Le; David Brizel; John Isitt; David Cella
Journal:  Cancer       Date:  2007-05-01       Impact factor: 6.860

6.  Burden of Oral Mucositis: A Systematic Review and Implications for Future Research.

Authors:  Karin Berger; Dorothee Schopohl; Antonia Bollig; Dorothea Strobach; Christina Rieger; Dale Rublee; Helmut Ostermann
Journal:  Oncol Res Treat       Date:  2018-05-03       Impact factor: 2.825

7.  Validation of a new scoring system for the assessment of clinical trial research of oral mucositis induced by radiation or chemotherapy. Mucositis Study Group.

Authors:  S T Sonis; J P Eilers; J B Epstein; F G LeVeque; W H Liggett; M T Mulagha; D E Peterson; A H Rose; M M Schubert; F K Spijkervet; J P Wittes
Journal:  Cancer       Date:  1999-05-15       Impact factor: 6.860

Review 8.  Guidelines for the assessment of oral mucositis in adult chemotherapy, radiotherapy and haematopoietic stem cell transplant patients.

Authors:  Barry Quinn; Carin M J Potting; Rebecca Stone; Nicole M A Blijlevens; Monica Fliedner; Anita Margulies; Lena Sharp
Journal:  Eur J Cancer       Date:  2007-11-07       Impact factor: 9.162

Review 9.  Perspectives on cancer therapy-induced mucosal injury: pathogenesis, measurement, epidemiology, and consequences for patients.

Authors:  Stephen T Sonis; Linda S Elting; Dorothy Keefe; Douglas E Peterson; Mark Schubert; Martin Hauer-Jensen; B Nebiyou Bekele; Judith Raber-Durlacher; J Peter Donnelly; Edward B Rubenstein
Journal:  Cancer       Date:  2004-05-01       Impact factor: 6.860

10.  Development and validation of a Patient-Reported Oral Mucositis Symptom (PROMS) scale.

Authors:  Jennifer A Kushner; Herenia P Lawrence; Irit Shoval; Thomas L Kiss; Gerald M Devins; Linda Lee; Howard C Tenenbaum
Journal:  J Can Dent Assoc       Date:  2008-02       Impact factor: 1.316

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  1 in total

1.  The incidence of severe oral mucositis in patients undergoing different conditioning regimens in haematopoietic stem cell transplantation.

Authors:  Midori Nakagaki; Glen A Kennedy; Nicole C Gavin; Alexandra Clavarino; Karen Whitfield
Journal:  Support Care Cancer       Date:  2022-08-26       Impact factor: 3.359

  1 in total

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