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Literature DB >> 34818874

Decoding m⁶A, one reader at a time.

Hanzhi Luo¹, Michael G Kharas².

Abstract

Entities: Chemical

Year: 2022 PMID： 34818874 PMCID： PMC9335108 DOI： 10.3324/haematol.2021.280166

Source DB: PubMed Journal: Haematologica ISSN： 0390-6078 Impact factor: 11.047

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14 in total

1. A Unified Model for the Function of YTHDF Proteins in Regulating m⁶A-Modified mRNA.

Authors: Sara Zaccara; Samie R Jaffrey
Journal: Cell Date: 2020-06-02 Impact factor: 41.582

2. Leukemogenic Chromatin Alterations Promote AML Leukemia Stem Cells via a KDM4C-ALKBH5-AXL Signaling Axis.

Authors: Jiazhen Wang; Yicun Li; Peipei Wang; Guoqiang Han; Tiantian Zhang; Jiwei Chang; Rong Yin; Yi Shan; Jin Wen; Xueqin Xie; Mengdie Feng; Qifan Wang; Jin Hu; Ying Cheng; Tong Zhang; Yashu Li; Zhuying Gao; Chengli Guo; Jing Wang; Jianfei Liang; Manman Cui; Kexin Gao; Jihua Chai; Weidong Liu; Hui Cheng; Lei Li; Fuling Zhou; Lingbo Liu; Yi Luo; Shaoguang Li; Haojian Zhang
Journal: Cell Stem Cell Date: 2020-05-12 Impact factor: 24.633

3. Promoter-bound METTL3 maintains myeloid leukaemia by m⁶A-dependent translation control.

Authors: Isaia Barbieri; Konstantinos Tzelepis; Luca Pandolfini; Junwei Shi; Gonzalo Millán-Zambrano; Samuel C Robson; Demetrios Aspris; Valentina Migliori; Andrew J Bannister; Namshik Han; Etienne De Braekeleer; Hannes Ponstingl; Alan Hendrick; Christopher R Vakoc; George S Vassiliou; Tony Kouzarides
Journal: Nature Date: 2017-11-27 Impact factor: 49.962

4. Small-molecule inhibition of METTL3 as a strategy against myeloid leukaemia.

Authors: Eliza Yankova; Wesley Blackaby; Mark Albertella; Justyna Rak; Etienne De Braekeleer; Georgia Tsagkogeorga; Ewa S Pilka; Demetrios Aspris; Dan Leggate; Alan G Hendrick; Natalie A Webster; Byron Andrews; Richard Fosbeary; Patrick Guest; Nerea Irigoyen; Maria Eleftheriou; Malgorzata Gozdecka; Joao M L Dias; Andrew J Bannister; Binje Vick; Irmela Jeremias; George S Vassiliou; Oliver Rausch; Konstantinos Tzelepis; Tony Kouzarides
Journal: Nature Date: 2021-04-26 Impact factor: 69.504

5. The N⁶-methyladenosine (m⁶A)-forming enzyme METTL3 controls myeloid differentiation of normal hematopoietic and leukemia cells.

Authors: Ly P Vu; Brian F Pickering; Yuanming Cheng; Sara Zaccara; Diu Nguyen; Gerard Minuesa; Timothy Chou; Arthur Chow; Yogesh Saletore; Matthew MacKay; Jessica Schulman; Christopher Famulare; Minal Patel; Virginia M Klimek; Francine E Garrett-Bakelman; Ari Melnick; Martin Carroll; Christopher E Mason; Samie R Jaffrey; Michael G Kharas
Journal: Nat Med Date: 2017-09-18 Impact factor: 53.440

6. Targeting the RNA m⁶A Reader YTHDF2 Selectively Compromises Cancer Stem Cells in Acute Myeloid Leukemia.

Authors: Jasmin Paris; Marcos Morgan; Joana Campos; Gary J Spencer; Alena Shmakova; Ivayla Ivanova; Christopher Mapperley; Hannah Lawson; David A Wotherspoon; Catarina Sepulveda; Milica Vukovic; Lewis Allen; Annika Sarapuu; Andrea Tavosanis; Amelie V Guitart; Arnaud Villacreces; Christian Much; Junho Choe; Ali Azar; Louie N van de Lagemaat; Douglas Vernimmen; Ali Nehme; Frederic Mazurier; Tim C P Somervaille; Richard I Gregory; Dónal O'Carroll; Kamil R Kranc
Journal: Cell Stem Cell Date: 2019-04-25 Impact factor: 24.633

7. m⁶A RNA Methylation Maintains Hematopoietic Stem Cell Identity and Symmetric Commitment.

Authors: Yuanming Cheng; Hanzhi Luo; Franco Izzo; Brian F Pickering; Diu Nguyen; Robert Myers; Alexandra Schurer; Saroj Gourkanti; Jens C Brüning; Ly P Vu; Samie R Jaffrey; Dan A Landau; Michael G Kharas
Journal: Cell Rep Date: 2019-08-13 Impact factor: 9.423

8. m⁶A reader Ythdf3 protects hematopoietic stem cell integrity under stress by promoting the translation of Foxm1 and Asxl1 transcripts.

Authors: Qinglin Dang; Qiong Wu; Fang Yu; Yue Sheng; Chunjie Yu; Guangzhong Song; Kimberly Paulsen; Jianxin Lyu; Zhijian Qian
Journal: Haematologica Date: 2022-08-01 Impact factor: 11.047

9. A critical role of nuclear m6A reader YTHDC1 in leukemogenesis by regulating MCM complex-mediated DNA replication.

Authors: Yue Sheng; Jiangbo Wei; Fang Yu; Huanzhou Xu; Chunjie Yu; Qiong Wu; Yin Liu; Lei Li; Xiao-Long Cui; Xueying Gu; Bin Shen; Wei Li; Yong Huang; Sumita Bhaduri-McIntosh; Chuan He; Zhijian Qian
Journal: Blood Date: 2021-12-30 Impact factor: 22.113

10. Targeting FTO Suppresses Cancer Stem Cell Maintenance and Immune Evasion.

Authors: Rui Su; Lei Dong; Yangchan Li; Min Gao; Li Han; Mark Wunderlich; Xiaolan Deng; Hongzhi Li; Yue Huang; Lei Gao; Chenying Li; Zhicong Zhao; Sean Robinson; Brandon Tan; Ying Qing; Xi Qin; Emily Prince; Jun Xie; Hanjun Qin; Wei Li; Chao Shen; Jie Sun; Prakash Kulkarni; Hengyou Weng; Huilin Huang; Zhenhua Chen; Bin Zhang; Xiwei Wu; Mark J Olsen; Markus Müschen; Guido Marcucci; Ravi Salgia; Ling Li; Amir T Fathi; Zejuan Li; James C Mulloy; Minjie Wei; David Horne; Jianjun Chen
Journal: Cancer Cell Date: 2020-06-11 Impact factor: 38.585