Literature DB >> 34818306

Opportunities and Challenges of Targeting an Aging Immune System.

Maximilian J Roesel1,2, Tomohisa Matsunaga1,3, Stefan G Tullius1.   

Abstract

Entities:  

Mesh：

Year:  2021        PMID： 34818306      PMCID： PMC9393903          DOI： 10.1097/TP.0000000000003930

Source DB:  PubMed          Journal:  Transplantation        ISSN： 0041-1337            Impact factor:   5.385


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  10 in total

1.  CD11c+ Dendritic Cells Accelerate the Rejection of Older Cardiac Transplants via Interleukin-17A.

Authors:  Rupert Oberhuber; Timm Heinbokel; Hector Rodriguez Cetina Biefer; Olaf Boenisch; Karin Hock; Roderick T Bronson; Markus J Wilhelm; Yoichiro Iwakura; Karoline Edtinger; Hirofumi Uehara; Markus Quante; Floris Voskuil; Felix Krenzien; Bendix Slegtenhorst; Reza Abdi; Johann Pratschke; Abdallah Elkhal; Stefan G Tullius
Journal:  Circulation       Date:  2015-05-08       Impact factor: 29.690

2.  Clearance of senescent cells by ABT263 rejuvenates aged hematopoietic stem cells in mice.

Authors:  Jianhui Chang; Yingying Wang; Lijian Shao; Remi-Martin Laberge; Marco Demaria; Judith Campisi; Krishnamurthy Janakiraman; Norman E Sharpless; Sheng Ding; Wei Feng; Yi Luo; Xiaoyan Wang; Nukhet Aykin-Burns; Kimberly Krager; Usha Ponnappan; Martin Hauer-Jensen; Aimin Meng; Daohong Zhou
Journal:  Nat Med       Date:  2015-12-14       Impact factor: 53.440

3.  Aged hematopoietic stem cells are refractory to bloodborne systemic rejuvenation interventions.

Authors:  Theodore T Ho; Paul V Dellorusso; Evgenia V Verovskaya; Sietske T Bakker; Johanna Flach; Lucas K Smith; Patrick B Ventura; Olivia M Lansinger; Aurélie Hérault; Si Yi Zhang; Yoon-A Kang; Carl A Mitchell; Saul A Villeda; Emmanuelle Passegué
Journal:  J Exp Med       Date:  2021-05-25       Impact factor: 14.307

Review 4.  Donor and Recipient Age-Mismatches: The Potential of Transferring Senescence.

Authors:  Jasper Iske; Tomohisa Matsunaga; Hao Zhou; Stefan G Tullius
Journal:  Front Immunol       Date:  2021-04-28       Impact factor: 7.561

5.  An aged immune system drives senescence and ageing of solid organs.

Authors:  Matthew J Yousefzadeh; Rafael R Flores; Yi Zhu; Zoe C Schmiechen; Robert W Brooks; Christy E Trussoni; Yuxiang Cui; Luise Angelini; Kyoo-A Lee; Sara J McGowan; Adam L Burrack; Dong Wang; Qing Dong; Aiping Lu; Tokio Sano; Ryan D O'Kelly; Collin A McGuckian; Jonathan I Kato; Michael P Bank; Erin A Wade; Smitha P S Pillai; Jenna Klug; Warren C Ladiges; Christin E Burd; Sara E Lewis; Nicholas F LaRusso; Nam V Vo; Yinsheng Wang; Eric E Kelley; Johnny Huard; Ingunn M Stromnes; Paul D Robbins; Laura J Niedernhofer
Journal:  Nature       Date:  2021-05-12       Impact factor: 69.504

6.  Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor.

Authors:  Jean-Philippe Coppé; Christopher K Patil; Francis Rodier; Yu Sun; Denise P Muñoz; Joshua Goldstein; Peter S Nelson; Pierre-Yves Desprez; Judith Campisi
Journal:  PLoS Biol       Date:  2008-12-02       Impact factor: 8.029

7.  Senolytics improve physical function and increase lifespan in old age.

Authors:  Ming Xu; Tamar Pirtskhalava; Joshua N Farr; Bettina M Weigand; Allyson K Palmer; Megan M Weivoda; Christina L Inman; Mikolaj B Ogrodnik; Christine M Hachfeld; Daniel G Fraser; Jennifer L Onken; Kurt O Johnson; Grace C Verzosa; Larissa G P Langhi; Moritz Weigl; Nino Giorgadze; Nathan K LeBrasseur; Jordan D Miller; Diana Jurk; Ravinder J Singh; David B Allison; Keisuke Ejima; Gene B Hubbard; Yuji Ikeno; Hajrunisa Cubro; Vesna D Garovic; Xiaonan Hou; S John Weroha; Paul D Robbins; Laura J Niedernhofer; Sundeep Khosla; Tamara Tchkonia; James L Kirkland
Journal:  Nat Med       Date:  2018-07-09       Impact factor: 53.440

Review 8.  Mechanisms and rejuvenation strategies for aged hematopoietic stem cells.

Authors:  Xia Li; Xiangjun Zeng; Yulin Xu; Binsheng Wang; Yanmin Zhao; Xiaoyu Lai; Pengxu Qian; He Huang
Journal:  J Hematol Oncol       Date:  2020-04-06       Impact factor: 17.388

Review 9.  Senolytic drugs: from discovery to translation.

Authors:  J L Kirkland; T Tchkonia
Journal:  J Intern Med       Date:  2020-08-04       Impact factor: 13.068

10.  Senolytics prevent mt-DNA-induced inflammation and promote the survival of aged organs following transplantation.

Authors:  Jasper Iske; Midas Seyda; Timm Heinbokel; Ryoichi Maenosono; Koichiro Minami; Yeqi Nian; Markus Quante; Christine S Falk; Haruhito Azuma; Friederike Martin; João F Passos; Claus U Niemann; Tamara Tchkonia; James L Kirkland; Abdallah Elkhal; Stefan G Tullius
Journal:  Nat Commun       Date:  2020-08-27       Impact factor: 14.919
  10 in total
  3 in total

Review 1.  Preserving and rejuvenating old organs for transplantation: novel treatments including the potential of senolytics.

Authors:  Tomohisa Matsunaga; Maximilian J Roesel; Andreas Schroeter; Yao Xiao; Hao Zhou; Stefan G Tullius
Journal:  Curr Opin Organ Transplant       Date:  2022-08-09       Impact factor: 2.269

Review 2.  Aging Affects the Role of Myeloid-Derived Suppressor Cells in Alloimmunity.

Authors:  Andreas Schroeter; Maximilian J Roesel; Tomohisa Matsunaga; Yao Xiao; Hao Zhou; Stefan G Tullius
Journal:  Front Immunol       Date:  2022-07-06       Impact factor: 8.786

Review 3.  Primary Graft Dysfunction: The Role of Aging in Lung Ischemia-Reperfusion Injury.

Authors:  Maximilian J Roesel; Nirmal S Sharma; Andreas Schroeter; Tomohisa Matsunaga; Yao Xiao; Hao Zhou; Stefan G Tullius
Journal:  Front Immunol       Date:  2022-05-24       Impact factor: 8.786
  3 in total

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