| Literature DB >> 34817844 |
Jiuqin Zhou1, Si Chen2, Lin Zhang1, Yongzhen Zhai3.
Abstract
Glucocorticoids are used as a first-line treatment for severe alcoholic hepatitis, and albumin reduces both the number of hospitalizations and mortality in patients with decompensated cirrhosis. However, for acute-on-chronic liver failure (ACLF), there is no definitive evidence that glucocorticoid therapy is beneficial. In this case report, we describe a male patient who developed into ACLF based on alcoholic cirrhosis, whose symptoms and clinical indicators continued to deteriorate after initial symptomatic treatment. The patient's condition gradually improved after low-dose glucocorticoid therapy, and long-term albumin supplementation resulted in a satisfactory outcome.Entities:
Keywords: Acute-on-chronic liver failure; Albumin; Alcoholic cirrhosis; Glucocorticoids; Spontaneous bacterial peritonitis
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Year: 2021 PMID: 34817844 PMCID: PMC9114176 DOI: 10.1007/s40199-021-00420-w
Source DB: PubMed Journal: Daru ISSN: 1560-8115 Impact factor: 4.088