Literature DB >> 3481460

Transurethral surgery in the treatment of invasive bladder cancer (T1 and T2).

H Wolf1, H G Iversen, P Rosenkilde, T Schrøder.   

Abstract

Ninety-nine primary transitional cell bladder tumours of categories T1 or T2 were treated by transurethral resection. 25% of these patients experienced a true recurrence indicating that surgery failed to control the tumour locally. These patients had a 5-year survival of 20%. We suspect that many of them did not have local disease when treated. Twenty-five % of the total patient population did not within five years get a new tumour. They were cured by the first transurethral resection. 30% of the patients experienced new non-invasive tumour growth that could be managed by repeated resections. These two groups of patients did extremely well, since the 5-year survival was equivalent to the 5-year survival of an age and sex matched control population. Thus, more than 50% of the patients benefitted from transurethral surgery. Less than 20% experienced a new invasive tumour growth. They are patients at risk of getting a progressive bladder cancer disease. 5-year survival of these patients was about 50%. We conclude that transitional cell bladder tumours of category T1 and some of category T2 are well treated by transurethral resection.

Entities:  

Mesh:

Year:  1987        PMID: 3481460

Source DB:  PubMed          Journal:  Scand J Urol Nephrol Suppl        ISSN: 0300-8886


  2 in total

Review 1.  High throughput molecular diagnostics in bladder cancer - on the brink of clinical utility.

Authors:  Karsten Zieger
Journal:  Mol Oncol       Date:  2007-12-08       Impact factor: 6.603

Review 2.  The role of a second transurethral resection for high-grade bladder cancer.

Authors:  P Langenstroer; W See
Journal:  Curr Urol Rep       Date:  2000-10       Impact factor: 2.862

  2 in total

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