Literature DB >> 3481431

Effect of transforming growth factor beta (TGF-beta) on ATP citrate lyase in isolated hepatocytes.

G Reinhart1, K Roehrig.   

Abstract

Transforming growth factor beta (TGF-beta) activates ATP citrate lyase in freshly isolated rat liver hepatocytes in a time dependent manner. Maximal stimulation of the enzyme occurred with less than thirty minutes of incubation of the cells with TGF-beta. The half-maximal effect on the enzyme determined in hepatocytes incubated with TGF-beta for 10 min at 37 degrees C was elicited by TGF-beta concentrations in the 10-11 - 10-12 M range. The potential role of TGF-beta stimulation of ATP citrate lyase activity in new membrane synthesis is discussed.

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Year:  1987        PMID： 3481431     DOI： 10.1007/BF00221920

Source DB:  PubMed          Journal:  Mol Cell Biochem        ISSN： 0300-8177            Impact factor:   3.396


  31 in total

1.  Regulation of ATP-citrate lyase in primary cultures of adult rat hepatocytes.

Authors:  J T Spence; H C Pitot; G Zalitis
Journal:  J Biol Chem       Date:  1979-12-10       Impact factor: 5.157

2.  Cellular receptors for type beta transforming growth factor. Ligand binding and affinity labeling in human and rodent cell lines.

Authors:  J Massagué; B Like
Journal:  J Biol Chem       Date:  1985-03-10       Impact factor: 5.157

3.  Transforming growth factor-beta inhibits endothelial cell proliferation.

Authors:  M Fràter-Schröder; G Müller; W Birchmeier; P Böhlen
Journal:  Biochem Biophys Res Commun       Date:  1986-05-29       Impact factor: 3.575

4.  Inhibition of endothelial cell proliferation by type beta-transforming growth factor: interactions with acidic and basic fibroblast growth factors.

Authors:  A Baird; T Durkin
Journal:  Biochem Biophys Res Commun       Date:  1986-07-16       Impact factor: 3.575

Review 5.  Short-term hormonal control of hepatic lipogenesis.

Authors:  M J Geelen; R A Harris; A C Beynen; S A McCune
Journal:  Diabetes       Date:  1980-12       Impact factor: 9.461

6.  Structure and properties of the cellular receptor for transforming growth factor type beta.

Authors:  B O Fanger; L M Wakefield; M B Sporn
Journal:  Biochemistry       Date:  1986-06-03       Impact factor: 3.162

7.  ATP-citrate lyase. Structure of a tryptic peptide containing the phosphorylation site directed by glucagon and the cAMP-dependent protein kinase.

Authors:  M W Pierce; J L Palmer; H T Keutmann; J Avruch
Journal:  J Biol Chem       Date:  1981-09-10       Impact factor: 5.157

8.  Effect of dietary state on hepatocyte size.

Authors:  B D Uhal; K L Roehrig
Journal:  Biosci Rep       Date:  1982-12       Impact factor: 3.840

9.  New class of transforming growth factors potentiated by epidermal growth factor: isolation from non-neoplastic tissues.

Authors:  A B Roberts; M A Anzano; L C Lamb; J M Smith; M B Sporn
Journal:  Proc Natl Acad Sci U S A       Date:  1981-09       Impact factor: 11.205

10.  Induction of lipogenic enzymes in primary cultures of rat hepatocytes. Relationship between lipogenesis and carbohydrate metabolism.

Authors:  J T Spence; H C Pitot
Journal:  Eur J Biochem       Date:  1982-11
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  1 in total

1.  Identification of c-Src tyrosine kinase substrates in platelet-derived growth factor receptor signaling.

Authors:  Ramars Amanchy; Jun Zhong; Rosa Hong; James H Kim; Marjan Gucek; Robert N Cole; Henrik Molina; Akhilesh Pandey
Journal:  Mol Oncol       Date:  2009-07-10       Impact factor: 6.603
  1 in total

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