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Literature DB >> 348130

Sequential studies in ankylosing spondylitis. Association of Klebsiella pneumoniae with active disease.

R W Ebringer, D R Cawdell, P Cowling, A Ebringer.

Abstract

A study of 163 patients with ankylosing spondylitis seen on 433 occasions showed that active inflammatory disease was strongly associated with the presence of Klebsiella pneumoniae in the faeces (P less than 0.001). Sequential studies showed that in patients with inactive disease the presence of a positive culture for Klebsiella was associated with the subsequent development of active inflammatory disease (P less than 0.001). These findings support the hypothesis that Kl. pneumoniae may be an initiating agent in ankylosing spondylitis.

Entities: Disease Species

Mesh：

Year: 1978 PMID： 348130 PMCID： PMC1001180 DOI： 10.1136/ard.37.2.146

Source DB: PubMed Journal: Ann Rheum Dis ISSN： 0003-4967 Impact factor: 19.103

14 in total

1. Yersinia-related arthritis in the Pacific Northwest.

Authors: D K Ford; E Henderson; G E Price; H B Stein
Journal: Arthritis Rheum Date: 1977 Jul-Aug

2. Antibody levels to enteric bacteria in juvenile rheumatoid arthritis.

Authors: G Gutowska-Grzegorczyk; J Baum
Journal: Arthritis Rheum Date: 1977-04

3. Cross reactions between human transplantation antigens and bacterial lipopolysaccharides.

Authors: A A Hirata; F C McIntire; P I Terasaki; K K Mittal
Journal: Transplantation Date: 1973-05 Impact factor: 4.939

4. HL-A, immune-response genes, and disease.

Authors: H O McDevitt; W F Bodmer
Journal: Lancet Date: 1974-06-22 Impact factor: 79.321

5. Gross reactivity between synthetic T,GA-L and transplantation antigens in CBA Mice.

Authors: A Ebringer; D A Davies
Journal: Nat New Biol Date: 1973-01-31

6. Lymphocyte abnormalities in ankylosing spondylitis.

Authors: P T Fan; P J Clements; D T Yu; G Opelz; R Bluestone
Journal: Ann Rheum Dis Date: 1977-10 Impact factor: 19.103

7. Immune response inversion after hyperimmunisation. Possible mechanism in the pathogenesis of HLA-linked diseases.

Authors: C R Young; A Ebringer; J R Archer
Journal: Ann Rheum Dis Date: 1978-04 Impact factor: 19.103

8. Necrotising enterocolitis despite breast feeding.

Authors: S H Reisner; B Garty
Journal: Lancet Date: 1977-09-03 Impact factor: 79.321

9. Ankylosing spondylitis: klebsiella and HL-A B27.

Authors: R Ebringer; D Cooke; D R Cawdell; P Cowling; A Ebringer
Journal: Rheumatol Rehabil Date: 1977-08

10. Immune function in ankylosing spondylitis: apparent relationship between streptococcal responses and HLA B27.

Authors: P J Zilko; M Thevathasan; R L Dawkins
Journal: J Rheumatol Suppl Date: 1977

85 in total

Review 1. [Rheumatology update. Current knowledge of etiology, pathophysiology, diagnosis, and therapy of selected arthritic disorders. Part I: pathogenesis and differential diagnosis].

Authors: G Hein; P Oelzner; H Sprott; B Manger
Journal: Med Klin (Munich) Date: 1999-09-15

Review 2. Small intestinal mucosal protection mechanisms and their importance in rheumatology.

Authors: S O'Mahony; A Ferguson
Journal: Ann Rheum Dis Date: 1991-05 Impact factor: 19.103

3. Enumeration of IgA producing cells by the enzyme linked immunospot (ELISPOT) technique to evaluate sulphasalazine effects in inflammatory arthritides.

Authors: N Feltelius; S Gudmundsson; L Wennersten; O Sjöberg; R Hällgren; L Klareskog
Journal: Ann Rheum Dis Date: 1991-06 Impact factor: 19.103

Review 4. Clinical, bacteriological, and serological aspects of Klebsiella infections and their spondylarthropathic sequelae.

Authors: H Sahly; R Podschun
Journal: Clin Diagn Lab Immunol Date: 1997-07