Literature DB >> 34806123

Functional survey of decellularized tissues transplantation for infertile females.

Mozafar Khazaei1, Mohammad Rasool Khazaei1, Morteza Alizadeh2, Shima Rahmati3, Leila Rezakhani4,5.   

Abstract

Numbers of women worldwide face infertility, which will have a significant impact on a couple's life. As a result, assisting with the treatment of these individuals is seen as a critical step. Successful births following uterus and ovary donation have been reported in recent. When immunosuppressive drugs are used in patients who receive donated tissues, there are always problems with the drugs' side effects. In recent years, tissue engineering has mainly been successful in treating infertility using decellularization techniques. Engineered uterus and ovary prevent immunological reactions and do not require immunosuppressive drugs. The most important aspect of using decellularized tissue is its proper function after transplantation. These tissues must be able to produce follicles, secrete hormones and cause pregnancy. This study aimed to investigate research on decellularized tissues and transplanted into the female reproductive system. In this study, just tissues that, after transplantation, have the proper function for fertility were investigated.
© 2021. The Author(s), under exclusive licence to Springer Nature B.V.

Entities:  

Keywords:  Decellularized tissue; Infertility; Reproductive system; Tissue engineering

Mesh:

Year:  2021        PMID: 34806123     DOI: 10.1007/s10561-021-09979-9

Source DB:  PubMed          Journal:  Cell Tissue Bank        ISSN: 1389-9333            Impact factor:   1.752


  2 in total

1.  STAT3 accelerates uterine epithelial regeneration in a mouse model of decellularized uterine matrix transplantation.

Authors:  Takehiro Hiraoka; Yasushi Hirota; Tomoko Saito-Fujita; Mitsunori Matsuo; Mahiro Egashira; Leona Matsumoto; Hirofumi Haraguchi; Sudhansu K Dey; Katsuko S Furukawa; Tomoyuki Fujii; Yutaka Osuga
Journal:  JCI Insight       Date:  2016-06-02

2.  Synergic effect of bee pollen and metformin on proliferation and apoptosis of granulosa cells: Rat model of polycystic ovary syndrome.

Authors:  Leila Naseri; Mohammad Rasool Khazaei; Mozafar Khazaei
Journal:  J Food Biochem       Date:  2021-02-08       Impact factor: 2.720

  2 in total
  1 in total

1.  Assessing the biocompatibility of bovine tendon scaffold, a step forward in tendon tissue engineering.

Authors:  Elahe Khakpour; Amin Tavassoli; Nasser Mahdavi-Shahri; Maryam M Matin
Journal:  Cell Tissue Bank       Date:  2022-05-21       Impact factor: 1.522

  1 in total

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