| Literature DB >> 34805421 |
Jacob D Feingold1, Erica L Swartwout1, Sacha A Roberts1, Benedict U Nwachukwu1, Anil S Ranawat1.
Abstract
BACKGROUND: Research has identified factors that influence achievement rates of threshold scores on patient-reported outcome measures (PROMs) after hip arthroscopy. However, little data exist on whether failure to achieve a threshold score (minimal clinically important difference [MCID] or substantial clinical benefit [SCB]) in the short term after hip arthroscopy predicts the risk of future hip surgery. PURPOSE/HYPOTHESIS: The purpose of this study was to determine if failure to achieve the MCID or SCB on PROMs within 1 year of hip arthroscopy can be considered a risk factor for repeat surgery within 5 years of primary hip arthroscopy. It was hypothesized that failure to achieve threshold scores would increase the risk of subsequent hip surgery. STUDYEntities:
Keywords: PROMs; femoroacetabular impingement; hip arthroscopy; hip preservation; sports medicine
Year: 2021 PMID: 34805421 PMCID: PMC8600560 DOI: 10.1177/23259671211053012
Source DB: PubMed Journal: Orthop J Sports Med ISSN: 2325-9671
Figure 1.Flowchart of patient inclusion and exclusion process for this study.
Patient Characteristics, Baseline PROMs, Surgical Indications, and Surgical Procedures
| Study Cohort (n = 88) | Control Cohort (n = 288) |
| |
|---|---|---|---|
| Sex | |||
| Male | 37 (42.0) | 138 (47.9) | .399 |
| Female | 51 (58.0) | 150 (52.1) | |
| Age, y | 33.1 (18-59) | 32.8 (18-57) | .804 |
| Baseline PROMs | |||
| HHS | 59.6 (12.1-95.7) | 63.1 (19.8-100) | .062 |
| HOS-ADL | 69.7 (13.2-97.1) | 72.7 (20.6-100) | .206 |
| HOS-Sports | 48.7 (0.00-100) | 48.9 (0.00-100) | .937 |
| iHOT-33 | 37.7 (2.2-78.6) | 38.5 (1.68-90.1) | .745 |
| Preoperative surgical indications | |||
| Labral tear | 73 (83.0) | 246 (85.4) | .588 |
| Pincer lesion | 25 (28.4) | 91 (31.6) | .567 |
| Cam lesion | 65 (73.9) | 231 (80.2) | .23 |
| Arthroscopic procedures | |||
| Labral repair | 60 (68.2) | 241 (83.7) |
|
| Labral debridement | 16 (18.2) | 43 (14.9) | .485 |
| Cam decompression | 68 (77.3) | 265 (92.0) |
|
| Rim decompression | 28 (31.8) | 117 (40.6) | .129 |
Data are reported as n (%) or mean (range). Bolded P values indicate a statistically significant difference between groups (P < .05). HOS-ADL, Hip Outcome Score–Activities of Daily Living; HOS-Sports, Hip Outcome Score–Sports; iHOT-33, 33-Item International Hip Outcome Tool; mHHS, modified Harris Hip Score; PROMs, patient-reported outcome measures.
Type and Time to Subsequent Surgery for the Study Cohort
| Type of Subsequent Surgery | No. of Patients (%) | Mean Months to Subsequent Surgery (range) |
|---|---|---|
| Overall study cohort | 88 (100) | 22.3 (5.5-59.3) |
| Total hip arthroplasty | 24 (27.3) | 26.4 (5.5-59.3) |
| Other | 64 (72.7) | 20.8 (6.0-51.7) |
Other subsequent surgeries included hip arthroscopy (n = 50), surgical hip dislocation (n = 6), periacetabular osteotomy (n = 5), excision of heterotopic ossification (n = 2), and gluteus medius repair (n = 1).
Postoperative Score and Percentage of Cohort to Achieve the MCID and SCB
| Study Cohort (n = 88) | Control Cohort (n = 288) |
| |
|---|---|---|---|
| Postoperative PROM score | |||
| mHHS | 62.1 (14.3-95.7) | 80.1 (29.7-100.1) | <.001 |
| HOS-ADL | 72.7 (17.7-100) | 87.7 (23.2-100) | <.001 |
| HOS-Sports | 46.6 (0.00-100) | 66.8 (0.00-100) | <.001 |
| iHOT-33 | 46.9 (0.43-94.7) | 68.5 (9.15-99.9) | <.001 |
| Achieved MCID | |||
| mHHS | 34.9 (30/86) | 70.5 (196/278) | <.001 |
| HOS-ADL | 36.0 (31/86) | 64.8 (184/284) | <.001 |
| HOS-Sports | 25.0 (21/84) | 53.3 (146/274) | <.001 |
| iHOT-33 | 40.6 (26/64) | 74.8 (166/222) | <.001 |
| Achieved SCB | |||
| mHHS | 17.4 (15/86) | 41.4 (115/278) | <.001 |
| HOS-ADL | 34.9 (30/86) | 60.2 (171/284) | <.001 |
| HOS-Sports | 11.9 (10/84) | 33.6 (92/274) | <.001 |
| iHOT-33 | 20.3 (13/64) | 55.4 (123/222) | <.001 |
Data are reported as mean (range) or % (n/total). All differences between groups were statistically significant (P < .05). iHOT-33, 33-Item International Hip Outcome Tool; HOS-ADL, Hip Outcome Score–Activities of Daily Living; HOS-Sports, Hip Outcome Score–Sports; MCID, minimal clinically important difference; mHHS, modified Harris Hip Score; PROM, patient-reported outcome measure; SCB, substantial clinical benefit.
Because MCID and SCB values are calculated as a change from baseline, a small number of patients with a high enough baseline score were unable to achieve the MCID/SCB.
Multivariable Logistic Regression for Subsequent Surgery Risk Controlling for Age, Sex, and Baseline PROMs
| (A) Subsequent Surgery Risk Based Off Not Achieving the MCID or SCB | ||
|---|---|---|
| OR (95% CI) |
| |
| MCID | ||
| mHHS | 5.39 (3.14-9.25) | <.001 |
| HOS-ADL | 5.20 (2.89-9.36) | <.001 |
| HOS-Sports | 4.02 (2.23-7.24) | <.001 |
| iHOT-33 | 4.78 (2.60-8.77) | <.001 |
| SCB | ||
| mHHS | 4.11 (2.19-7.72) | <.001 |
| HOS-ADL | 4.69 (2.58-8.51) | <.001 |
| HOS-Sports | 4.57 (2.14-9.74) | <.001 |
| iHOT-33 | 5.20 (2.65-10.2) | <.001 |
| (B) Cumulative Subsequent Surgery Risk for Not Achieving the MCID or SCB on Multiple PROMs | ||
| OR (95% CI) |
| |
| MCID | 1.68 (1.42-1.98) | <.001 |
| SCB | 1.63 (1.35-1.97) | <.001 |
Part A shows the risk of revision surgery associated with failure to achieve the MCID or SCB on any PROM. Part B shows the risk of revision surgery associated with the cumulative effect of failure to achieve the MCID or SCB on multiple PROMs. All results were statistically significant (P < .05). iHOT-33, 33-Item International Hip Outcome Tool; HOS-ADL, Hip Outcome Score–Activities of Daily Living; HOS-Sports, Hip Outcome Score–Sports; MCID, minimal clinically important difference; mHHS, modified Harris Hip Score; PROM, patient-reported outcome measure; SCB, substantial clinical benefit.
Sensitivity, Specificity, Positive Likelihood Ratio, and Negative Likelihood Ratio for the PROMs Evaluated
| mHHS | HOS-ADL | HOS-Sport | iHOT-33 | |
|---|---|---|---|---|
| MCID | ||||
| Sensitivity | 0.41 (0.33-0.49) | 0.35 (0.28-0.43) | 0.33 (0.26-0.40) | 0.40 (0.31-0.51) |
| Specificity | 0.87 (0.82-0.91) | 0.86 (0.81-0.90) | 0.87 (0.81-0.92) | 0.86 (0.81-0.91) |
| LR+ | 3.06 (2.12-4.67) | 2.46 (1.71-3.75) | 2.62 (1.66-4.07) | 2.99 (1.99-4.80) |
| LR– | 0.69 (0.59-0.79) | 0.75 (0.66-0.85) | 0.77 (0.69-0.86) | 0.69 (0.58-0.82) |
| SCB | ||||
| Sensitivity | 0.30 (0.25-0.37) | 0.33 (0.26-0.40) | 0.29 (0.23-0.35) | 0.34 (0.27-0.42) |
| Specificity | 0.88 (0.82-0.94) | 0.85 (0.79-0.89) | 0.91 (0.83-0.95) | 0.90 (0.85-0.95) |
| LR+ | 2.62 (1.64-4.76) | 2.22 (1.48-3.26) | 2.95 (1.57-5.43) | 3.55 (2.13-6.86) |
| LR– | 0.79 (0.70-0.87) | 0.79 (0.70-0.89) | 0.79 (0.72-0.88) | 0.73 (0.64-0.82) |
Data in parentheses are 95% CIs. Sensitivity, specificity, LR+, and LR– were calculated as follows:
HOS-ADL, Hip Outcome Score-Activities of Daily Living; HOS-Sports, Hip Outcome Score-Sports; iHOT-33, 33-Item International Hip Outcome Tool; MCID, minimal clinically important difference; mHHS, modified Harris Hip Score; LR+, positive likelihood ratio; LR–, negative likelihood ratio; PROM, patient-reported outcome measure; SCB, substantial clinical benefit.