| Literature DB >> 34796277 |
Warwick Grant1, Stephen R Doyle2, Kirsty McCann1.
Abstract
We present a genome assembly and annotation of an individual female Cercopithifilaria johnstoni, a parasitic filarial nematode that is transmitted by hard ticks (Ixodidae) to infect a broad range of native Australian murid and marsupial hosts. The genome sequence is 76.9 Mbp in length, and although in draft form (N50 = 99 kbp, N50[n] = 232), is largely complete based on universally conserved orthologs (BUSCOs; genome = 94.9%, protein = 96.5%) and relative to other related filarial species. These data represent the first genomic resources for the genus Cercopithifilaria, a group of parasites with a broad host range, and form the basis for comparative analysis with the human-infective parasite, Onchocerca volvulus, both of which are responsible for similar eye and skin pathologies in their respective hosts. Copyright:Entities:
Keywords: Cercopithifilaria johnstoni; Illumina MiSeq; filarial nematode; genome assembly
Year: 2021 PMID: 34796277 PMCID: PMC8564745.2 DOI: 10.12688/wellcomeopenres.17258.2
Source DB: PubMed Journal: Wellcome Open Res ISSN: 2398-502X