Literature DB >> 34793964

Autoimmunity May Explain Diabetes in a Subset of Patients With Recurrent Acute and Chronic Pancreatitis: A Pilot Study.

Dhiraj Yadav1, David C Whitcomb2, Gong Tang3, Adam Slivka4, Melena Bellin5.   

Abstract

Pancreatogenic diabetes mellitus, also termed type 3c diabetes (T3cD), or glucose intolerance develops in 25%-75% of adults with chronic pancreatitis (CP). The primary pathophysiologic defect in T3cD is insulin deficiency, thought to result largely from "bystander" injury to the islets from fibrotic changes in the exocrine pancreas and cytokine-induced beta cell dysfunction from intrapancreatic inflammation.1.
Copyright © 2021 AGA Institute. Published by Elsevier Inc. All rights reserved.

Entities:  

Year:  2021        PMID： 34793964     DOI： 10.1016/j.cgh.2021.11.011

Source DB:  PubMed          Journal:  Clin Gastroenterol Hepatol        ISSN： 1542-3565            Impact factor:   11.382


  5 in total

Review 1.  The spectrum of diabetes in acute and chronic pancreatitis.

Authors:  Søren S Olesen; Frederico G S Toledo; Phil A Hart
Journal:  Curr Opin Gastroenterol       Date:  2022-07-18       Impact factor: 2.741

2.  Rationale and Design for the Diabetes RElated to Acute Pancreatitis and Its Mechanisms Study: A Prospective Cohort Study From the Type 1 Diabetes in Acute Pancreatitis Consortium.

Authors:  Phil A Hart; Georgios I Papachristou; Walter G Park; Anne-Marie Dyer; Vernon M Chinchilli; Elham Afghani; Venkata S Akshintala; Dana K Andersen; James L Buxbaum; Darwin L Conwell; Kathleen M Dungan; Jeffrey J Easler; Evan L Fogel; Carla J Greenbaum; Rita R Kalyani; Murray Korc; Richard Kozarek; Maren R Laughlin; Peter J Lee; Jennifer L Maranki; Stephen J Pandol; Anna Evans Phillips; Jose Serrano; Vikesh K Singh; Cate Speake; Temel Tirkes; Frederico G S Toledo; Guru Trikudanathan; Santhi Swaroop Vege; Ming Wang; Cemal Yazici; Atif Zaheer; Christopher E Forsmark; Melena D Bellin; Dhiraj Yadav
Journal:  Pancreas       Date:  2022-07-01       Impact factor: 3.243

3.  Evaluating the Immunopathogenesis of Diabetes After Acute Pancreatitis in the Diabetes RElated to Acute Pancreatitis and Its Mechanisms Study: From the Type 1 Diabetes in Acute Pancreatitis Consortium.

Authors:  Anna Casu; Paul J Grippo; Clive Wasserfall; Zhaoli Sun; Peter S Linsley; Jessica A Hamerman; Brian T Fife; Adam Lacy-Hulbert; Frederico G S Toledo; Phil A Hart; Georgios I Papachristou; Melena D Bellin; Dhiraj Yadav; Maren R Laughlin; Mark O Goodarzi; Cate Speake
Journal:  Pancreas       Date:  2022-07-01       Impact factor: 3.243

4.  Assessing the Pathophysiology of Hyperglycemia in the Diabetes RElated to Acute Pancreatitis and Its Mechanisms Study: From the Type 1 Diabetes in Acute Pancreatitis Consortium.

Authors:  Kathleen M Dungan; Phil A Hart; Dana K Andersen; Marina Basina; Vernon M Chinchilli; Kirstie K Danielson; Carmella Evans-Molina; Mark O Goodarzi; Carla J Greenbaum; Rita R Kalyani; Maren R Laughlin; Ariana Pichardo-Lowden; Richard E Pratley; Jose Serrano; Emily K Sims; Cate Speake; Dhiraj Yadav; Melena D Bellin; Frederico G S Toledo
Journal:  Pancreas       Date:  2022-07-01       Impact factor: 3.243

Review 5.  Pancreatogenic Diabetes in Children With Recurrent Acute and Chronic Pancreatitis: Risks, Screening, and Treatment (Mini-Review).

Authors:  Melena D Bellin
Journal:  Front Pediatr       Date:  2022-04-26       Impact factor: 3.418
  5 in total

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