Literature DB >> 3479332

Transient gene expression in untransformed lymphocytes.

I L Mårtensson1, T Leanderson.   

Abstract

Conditions for transfection of normal, freshly isolated and mitogen-stimulated spleen cells were established. A sharp optimum of plasmid at 10 micrograms per 1.5 X 10(7) transfected spleen cells per transfection was observed. The Ig promoter and the IgH enhancer activity was found to be restricted to cells of the B lineage also in normal, freshly isolated lymphocytes in vitro.

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Year:  1987        PMID: 3479332     DOI: 10.1002/eji.1830171017

Source DB:  PubMed          Journal:  Eur J Immunol        ISSN: 0014-2980            Impact factor:   5.532


  6 in total

1.  Functional modularity in the SP6 kappa promoter.

Authors:  E Högbom; A C Magnusson; T Leanderson
Journal:  Nucleic Acids Res       Date:  1991-08-25       Impact factor: 16.971

2.  The chicken immunoglobulin lambda light chain gene is transcriptionally controlled by a modularly organized enhancer and an octamer-dependent silencer.

Authors:  S Bulfone-Paus; L Reiners-Schramm; R Lauster
Journal:  Nucleic Acids Res       Date:  1995-06-11       Impact factor: 16.971

3.  The c-myc protein represses the lambda 5 and TdT initiators.

Authors:  S Mai; I L Mårtensson
Journal:  Nucleic Acids Res       Date:  1995-01-11       Impact factor: 16.971

4.  Lymphocyte expression in transgenic trout by mouse immunoglobulin promoter/enhancer.

Authors:  C Michard-Vanhée; D Chourrout; S Strömberg; A Thuvander; L Pilström
Journal:  Immunogenetics       Date:  1994       Impact factor: 2.846

5.  Promoter, enhancer and silencer elements regulate rearrangement of an immunoglobulin transgene.

Authors:  R Lauster; C A Reynaud; I L Mårtensson; A Peter; D Bucchini; J Jami; J C Weill
Journal:  EMBO J       Date:  1993-12       Impact factor: 11.598

6.  The structure of an alternate form of complement C3 that displays costimulatory growth factor activity for B lymphocytes.

Authors:  Y Cahen-Kramer; I L Mårtensson; F Melchers
Journal:  J Exp Med       Date:  1994-12-01       Impact factor: 14.307

  6 in total

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