Naoki Kaneko1, Ariel Takayanagi1,2, Hamidreza Saber1, Lea Guo1, Satoshi Tateshima1. 1. Department of Radiological Sciences, David Geffen School of Medicine, 8783University of California Los Angeles, Los Angeles, CA, USA. 2. Department of Neurological Surgery, 472028Riverside University Health System, Moreno Valley, CA, USA.
Abstract
OBJECTIVE: Neuroendovascular procedures rely on successful navigation and stable access to the target vessel. The Stabilizer is a 300 cm long exchange wire with a 0.014 diameter and a soft, flexible stent at the distal end designed to assist with navigation and device delivery. This study aims to assess the efficacy of the Stabilizer for navigation in a variety of challenging environments. METHODS: The efficacy of the Stabilizer was evaluated using three challenging vascular models: a giant aneurysm model, a severe tortuosity model, and an M1 stenosis model. The Stabilizer was compared with a conventional wire during navigation in each model. RESULTS: In the giant aneurysm model, there was no significant difference of success during straightening of a looped wire and significantly higher success rates when advancing an intermediate catheter with the Stabilizer beyond the aneurysm neck compared to a conventional guidewire. The Stabilizer also significantly increased success rates when advancing an intermediate catheter through a model with severe tortuosity compared to a conventional guidewire, as well as exchange maneuver for intracranial stenting in a stenosis model compared to an exchange wire. CONCLUSIONS: In our experimental model, the Stabilizer significantly improved navigation and device delivery in a variety of challenging settings compared to conventional wires.
OBJECTIVE: Neuroendovascular procedures rely on successful navigation and stable access to the target vessel. The Stabilizer is a 300 cm long exchange wire with a 0.014 diameter and a soft, flexible stent at the distal end designed to assist with navigation and device delivery. This study aims to assess the efficacy of the Stabilizer for navigation in a variety of challenging environments. METHODS: The efficacy of the Stabilizer was evaluated using three challenging vascular models: a giant aneurysm model, a severe tortuosity model, and an M1 stenosis model. The Stabilizer was compared with a conventional wire during navigation in each model. RESULTS: In the giant aneurysm model, there was no significant difference of success during straightening of a looped wire and significantly higher success rates when advancing an intermediate catheter with the Stabilizer beyond the aneurysm neck compared to a conventional guidewire. The Stabilizer also significantly increased success rates when advancing an intermediate catheter through a model with severe tortuosity compared to a conventional guidewire, as well as exchange maneuver for intracranial stenting in a stenosis model compared to an exchange wire. CONCLUSIONS: In our experimental model, the Stabilizer significantly improved navigation and device delivery in a variety of challenging settings compared to conventional wires.
Authors: Ferdinand K Hui; Muhammad S Hussain; Alejandro Spiotta; Tarun Bhalla; Gabor Toth; Shaye I Moskowitz; Mohamed Elgabaly; Thinesh Sivapatham; Peter A Rasmussen Journal: Neurosurgery Date: 2012-02 Impact factor: 4.654
Authors: Johnny H Y Wong; Huy M Do; Nicholas A Telischak; Adrienne M Moraff; Robert L Dodd; Michael P Marks; Shreya M Ingle; Jeremy J Heit Journal: J Neurointerv Surg Date: 2016-10-27 Impact factor: 5.836