Literature DB >> 34785123

Mini CRISPR-Cas12f1: a new genome editing tool.

Muhammad Jawad Akbar Awan1, Imran Amin1, Shahid Mansoor2.   

Abstract

The clustered regularly interspaced short palindromic repeats and associated protein (CRISPR-Cas) toolbox enables targeted mutations to be introduced into a genome. However, the delivery of appropriately sized Cas effectors to develop transgene-free edited plants is a limiting factor. A novel mini CRISPR-Cas12f1 system recently reported by Wu et al. overcomes this challenge by deploying viral-based vectors and nanoparticles (NPs) as carriers.
Copyright © 2021 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  AsCas12f1; genome editing; nanoparticles; transgene free editing; viral vectors

Mesh：

Year:  2021        PMID： 34785123     DOI： 10.1016/j.tplants.2021.11.002

Source DB:  PubMed          Journal:  Trends Plant Sci        ISSN： 1360-1385            Impact factor:   18.313


  3 in total

Review 1.  Efficient Genome Editing by a Miniature CRISPR-AsCas12f1 Nuclease in Bacillus anthracis.

Authors:  Yanchun Wang; Shuli Sang; Xin Zhang; Haoxia Tao; Qing Guan; Chunjie Liu
Journal:  Front Bioeng Biotechnol       Date:  2022-01-14

2.  Tobacco Rattle Virus as a Tool for Rapid Reverse-Genetics Screens and Analysis of Gene Function in Cannabis sativa L.

Authors:  Hanan Alter; Reut Peer; Aviv Dombrovsky; Moshe Flaishman; Ben Spitzer-Rimon
Journal:  Plants (Basel)       Date:  2022-01-26

Review 3.  Enabling Trade in Gene-Edited Produce in Asia and Australasia: The Developing Regulatory Landscape and Future Perspectives.

Authors:  Michael G K Jones; John Fosu-Nyarko; Sadia Iqbal; Muhammad Adeel; Rhodora Romero-Aldemita; Mahaletchumy Arujanan; Mieko Kasai; Xun Wei; Bambang Prasetya; Satya Nugroho; Osman Mewett; Shahid Mansoor; Muhammad J A Awan; Reynante L Ordonio; S R Rao; Abhijit Poddar; Penny Hundleby; Nipon Iamsupasit; Kay Khoo
Journal:  Plants (Basel)       Date:  2022-09-27
  3 in total

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