Yu Xue Wang1, Li Zhang2, Chun Jun Li3, Xin Qi3, Ya Qi Fan1, Jiang Shan He1, Pei Guo1, Jia Lin Hu1, Shuo Chen4, Yu Jie Niu5, Feng Liu4, Rong Zhang5, Qiang Li4, Shi Tao Ma5, Mian Zhi Zhang6, Cheng Lin Hong7, Min Ying Zhang1. 1. School of Medicine, Nankai University, Tianjin 300071, China. 2. Tianjin First Central Hospital, Tianjin 300071, China. 3. Tianjin Union Medical Center, Tianjin 300071, China. 4. Beijing Physical Examination Center, Beijing 100021, China. 5. Hebei Key Laboratory of Environment and Human Health, Shijiazhuang 050000, Hebei, China;Department of Occupational Health and Environmental Health, Hebei Medical University, Shijiazhuang 050000, Hebei, China. 6. Dongfang Hospital, Beijing University of Chinese Medicine, Beijing 100071, China;Tianjin Academy of Traditional Chinese Medicine Affiliated Hospital, Tianjin 300120, China. 7. Department of Social Welfare, School of Public Affairs, University of California, Los Angeles 90095, CA, America.
Abstract
OBJECTIVE: The study aims to predict 10-year cardiovascular disease (CVD) risk and explore its association with sleep duration among Chinese urban adults. METHODS: We analyzed part of the baseline data of a cohort that recruited adults for health screening by cluster sampling. The simplified Pittsburgh Sleep Quality Index (PSQI) and Framingham 10-year risk score (FRS) were used to measure sleep duration and CVD risk. Demographic characteristics, personal history of chronic diseases, lifestyle factors were collected using a questionnaire. Height, weight, total cholesterol (TC), and high-density lipoprotein cholesterol (HDL-C) were also measured. Multiple logistic regression models were performed to explore the association of sleep duration with the predicted CVD risk. RESULTS: We included 31, 135 participants (median age 44 years, 53.02% males) free of CVD, cerebral stroke, and not taking lipid-lowering agents. Overall, 14.05%, and 25.55% of participants were at medium and high predicted CVD risk, respectively. Short sleep was independently associated with increased odds of medium to high risk of predicted 10-year CVD among males ( OR = 1.10; 95% CI: 1.01-1.19) and increased odds of medium to high and high risk of predicted 10-year CVD among females ( OR = 1.23; 95% CI: 1.08-1.40; OR = 1.27; 95% CI: 1.11-1.44). In contrast, long sleep had no association with cardiovascular risk. CONCLUSION: A substantial number of adults free of CVD were at high 10-year CVD risk. Short sleep was associated with increased odds of predicted CVD risk.
OBJECTIVE: The study aims to predict 10-year cardiovascular disease (CVD) risk and explore its association with sleep duration among Chinese urban adults. METHODS: We analyzed part of the baseline data of a cohort that recruited adults for health screening by cluster sampling. The simplified Pittsburgh Sleep Quality Index (PSQI) and Framingham 10-year risk score (FRS) were used to measure sleep duration and CVD risk. Demographic characteristics, personal history of chronic diseases, lifestyle factors were collected using a questionnaire. Height, weight, total cholesterol (TC), and high-density lipoprotein cholesterol (HDL-C) were also measured. Multiple logistic regression models were performed to explore the association of sleep duration with the predicted CVD risk. RESULTS: We included 31, 135 participants (median age 44 years, 53.02% males) free of CVD, cerebral stroke, and not taking lipid-lowering agents. Overall, 14.05%, and 25.55% of participants were at medium and high predicted CVD risk, respectively. Short sleep was independently associated with increased odds of medium to high risk of predicted 10-year CVD among males ( OR = 1.10; 95% CI: 1.01-1.19) and increased odds of medium to high and high risk of predicted 10-year CVD among females ( OR = 1.23; 95% CI: 1.08-1.40; OR = 1.27; 95% CI: 1.11-1.44). In contrast, long sleep had no association with cardiovascular risk. CONCLUSION: A substantial number of adults free of CVD were at high 10-year CVD risk. Short sleep was associated with increased odds of predicted CVD risk.