Literature DB >> 3478129

Duplication of Ph and of 9q+ chromosomes during the blastic transformation of a CML case.

G C Avanzi1, B Giovinazzo, G Saglio, A Guerrasio, A Rosso, M Bertini, L Resegotti, L Pegoraro.   

Abstract

We describe the blastic transformation of a case of chronic myelocytic leukemia in which, among other abnormalities, one extra Philadelphia and one extra 9q+ were observed. Molecular studies and analysis of the clonal evolution of the karyotype led to the interpretation of such an unusual finding as the result of nondisjunction, rather than of a double t(9;22) translocation.

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Year:  1987        PMID: 3478129     DOI: 10.1016/0165-4608(87)90030-6

Source DB:  PubMed          Journal:  Cancer Genet Cytogenet        ISSN: 0165-4608


  1 in total

1.  A case of hypoplastic chronic myelogenous leukemia initiating with pancytopenia.

Authors:  Mitsuhiro Matsuda; Hajime Miyazato; Satomi Ueda; Yasuyoshi Morita; Mika Sakaguchi; Yoichi Tatsumi; Yasuhiro Maeda; Akihisa Kanamaru
Journal:  Int J Hematol       Date:  2002-04       Impact factor: 2.490

  1 in total

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