| Literature DB >> 3478124 |
S Heim1, G Alimena, R Billström, D Diverio, U Kristoffersson, N Mandahl, M Nanni, F Mitelman.
Abstract
Tetraploid karyotypes without structural chromosome abnormalities were found in approximately 50% of the bone marrow cells in two patients with acute lymphoblastic leukemia with L2 morphology and "null cell" immunophenotype. Strict tetraploidy (4n = 92) has not been reported as the sole karyotypic rearrangement in bone marrow neoplasia, but may represent a previously unrecognized cytogenetic leukemia subtype.Entities:
Mesh：
Year: 1987 PMID： 3478124 DOI： 10.1016/0165-4608(87)90039-2
Source DB: PubMed Journal: Cancer Genet Cytogenet ISSN： 0165-4608