Tatiana Onofre1,2, Nicole Oliver3, Renata Carlos3, Davi Fialho3, Renata C Corte3, Amanda Felismino3, Eliane P da Silva4, Selma Bruno5. 1. Physical Therapy Department, Federal University of Paraíba, Campus I - Lot, Cidade Universitária, João Pessoa, Paraíba, 58051-900, Brazil. tatianaonofre@hotmail.com. 2. Cardiovascular and Metabolic Rehabilitation Laboratory, Postgraduate Physical Therapy Program, Physical Therapy Department, Federal University of Rio Grande Do Norte, Caixa Postal 1524, Campus Universitário, Lagoa Nova, Natal, Rio Grande do Norte, 59078-900, Brazil. tatianaonofre@hotmail.com. 3. Cardiovascular and Metabolic Rehabilitation Laboratory, Postgraduate Physical Therapy Program, Physical Therapy Department, Federal University of Rio Grande Do Norte, Caixa Postal 1524, Campus Universitário, Lagoa Nova, Natal, Rio Grande do Norte, 59078-900, Brazil. 4. Integrated Medicine Department, Federal University of Rio Grande Do Norte, Caixa Postal 1524, Campus Universitário, Lagoa Nova, Natal, Rio Grande do Norte, 59078-900, Brazil. 5. Cardiovascular and Metabolic Rehabilitation Laboratory, Physical Therapy Department, Federal University of Rio Grande Do Norte, Caixa Postal 1524, Campus Universitário, Lagoa Nova, Natal, Rio Grande do Norte, 59078-900, Brazil.
Abstract
PURPOSE: Bariatric surgery is effective in controlling severe obesity. However, studies investigating the impact of surgically induced weight loss on cardiorespiratory and metabolic responses during maximal effort are controversial. The aim of this study was to assess cardiorespiratory and metabolic responses in women with obesity after bariatric surgery. MATERIALS AND METHODS: We performed a secondary analysis on data from a pilot study with women with obesity submitted to bariatric surgery and who did not participate in a controlled physical training program. Anthropometry, pulmonary function (spirometry), and cardiorespiratory fitness (cardiopulmonary exercise testing [CPX]) were assessed before and after bariatric surgery. RESULTS: Thirty-four women were included (38.7 ± 9.6 years, body mass index = 44.1 ± 6.3 kg/m2). Postoperative assessment was conducted 9.4 ± 2.7 months after surgery. After surgery, we observed a reduction in all anthropometric measurements (mean loss of 28.6 kg, p < 0.001), and improvement in spirometry values (p < 0.001). Relative VO2peak (mL/kg/min) increased slightly (Δ = 1.7; p = 0.06); however, absolute VO2peak (L/min) reduced significantly (Δ = - 0.398; p < 0.001). We also observed an increase of 1.3 min (p < 0.001) in CPX duration, a reduction of 11.3 bpm (p < 0.001) in resting heart rate, and a decrease of systolic (p = 0.02) and diastolic (p < 0.001) blood pressures at peak effort. CONCLUSION: Surgically induced weight loss without exercise training improved cardiac reserve, ventilatory response, blood pressure, and resting heart rate. Cardiorespiratory fitness reflected by relative VO2peak increased slightly, despite increased tolerance to CPX.
PURPOSE: Bariatric surgery is effective in controlling severe obesity. However, studies investigating the impact of surgically induced weight loss on cardiorespiratory and metabolic responses during maximal effort are controversial. The aim of this study was to assess cardiorespiratory and metabolic responses in women with obesity after bariatric surgery. MATERIALS AND METHODS: We performed a secondary analysis on data from a pilot study with women with obesity submitted to bariatric surgery and who did not participate in a controlled physical training program. Anthropometry, pulmonary function (spirometry), and cardiorespiratory fitness (cardiopulmonary exercise testing [CPX]) were assessed before and after bariatric surgery. RESULTS: Thirty-four women were included (38.7 ± 9.6 years, body mass index = 44.1 ± 6.3 kg/m2). Postoperative assessment was conducted 9.4 ± 2.7 months after surgery. After surgery, we observed a reduction in all anthropometric measurements (mean loss of 28.6 kg, p < 0.001), and improvement in spirometry values (p < 0.001). Relative VO2peak (mL/kg/min) increased slightly (Δ = 1.7; p = 0.06); however, absolute VO2peak (L/min) reduced significantly (Δ = - 0.398; p < 0.001). We also observed an increase of 1.3 min (p < 0.001) in CPX duration, a reduction of 11.3 bpm (p < 0.001) in resting heart rate, and a decrease of systolic (p = 0.02) and diastolic (p < 0.001) blood pressures at peak effort. CONCLUSION: Surgically induced weight loss without exercise training improved cardiac reserve, ventilatory response, blood pressure, and resting heart rate. Cardiorespiratory fitness reflected by relative VO2peak increased slightly, despite increased tolerance to CPX.
Authors: Donald M Lloyd-Jones; Yuling Hong; Darwin Labarthe; Dariush Mozaffarian; Lawrence J Appel; Linda Van Horn; Kurt Greenlund; Stephen Daniels; Graham Nichol; Gordon F Tomaselli; Donna K Arnett; Gregg C Fonarow; P Michael Ho; Michael S Lauer; Frederick A Masoudi; Rose Marie Robertson; Véronique Roger; Lee H Schwamm; Paul Sorlie; Clyde W Yancy; Wayne D Rosamond Journal: Circulation Date: 2010-01-20 Impact factor: 29.690
Authors: Diana L Alba; Lucy Wu; Peggy M Cawthon; Kathleen Mulligan; Thomas Lang; Sheena Patel; Nicole J King; Jonathan T Carter; Stanley J Rogers; Andrew M Posselt; Lygia Stewart; Dolores M Shoback; Anne L Schafer Journal: J Clin Endocrinol Metab Date: 2019-03-01 Impact factor: 5.958
Authors: Ross Arena; Justin M Canada; Dejana Popovic; Cory R Trankle; Marco Giuseppe Del Buono; Alexander Lucas; Antonio Abbate Journal: Expert Rev Cardiovasc Ther Date: 2020-08-20