Babangida Chori1, Benjamin Danladi1, Peter Nwakile2, Innocent Okoye3, Umar Abdullahi4, Kefas Zawaya5, Ime Essien6, Kabiru Sada4, Maxwell Nwegbu7, John Ogedengbe8, Akinyemi Aje9, Godsent Isiguzo10, Augustine Odili11. 1. Circulatory Health Research Laboratory, College of Health Sciences, University of Abuja, Abuja, Nigeria. 2. Department of Community Health, University of Uyo Teaching Hospital, Uyo, Akwa Ibom, Nigeria. 3. Department of Medicine, Chukwuemeka Odumegwu University, Awka, Anambra, Nigeria. 4. Department of Medicine, Federal Medical Centre, Gusau, Zamfara, Nigeria. 5. Department of Medicine, Federal Teaching Hospital Gombe, Gombe, Nigeria. 6. Department of Medicine, University of Uyo, Akwa Ibom, Nigeria. 7. Department of Chemical Pathology, Faculty of Basic Clinical Sciences, University of Abuja, Abuja, Nigeria. 8. Department of Human Physiology, Faculty of Basic Medical Sciences, University of Abuja, Abuja, Nigeria. 9. Department of Medicine, University College Hospital, Ibadan, Oyo, Nigeria. 10. Department of Medicine, Federal University Teaching Hospital, Abakaliki, Ebonyi, Nigeria. 11. Circulatory Health Research Laboratory, College of Health Sciences, University of Abuja; Beside School of Nursing, University of Abuja Teaching Hospital, Gwagwalada, Abuja, Nigeria. Email: augustine.odili@uniabuja.edu.ng.
Abstract
AIM: The aim of this study was to determine the prevalence and predictors of dyslipidaemia in adults in Nigeria. METHODS: Using the WHO criteria, we determined dyslipidaemia using serum lipid levels of 3 211 adult Nigerians, aged at least 18 years, obtained between March 2017 and February 2018 from two communities (rural and urban) in a state from each of the six geopolitical zones of Nigeria. RESULTS: The overall prevalence of low high-density lipoprotein cholesterol (l-HDL), elevated low-density lipoprotein cholesterol (e-LDL), hypertriglyceridaemia (h-TG) and hypercholesterolaemia (h-CHL) were 72.5,13.6, 21.4 and 7.5%, respectively. The adjusted odds of h-CHL [odds ratio (95% confidence interval) 1.47 (1.10-1.95)], h-TG [1.89 (1.48-2.41)] and e-LDL [1.51 (1.03-2.15)] increased with obesity. Being a rural dweller increased the odds of h-TG [1.55 (1.29-1.85)], e-LDL [1.38 (1.10-1.73)] and l-HDL [1.34 (1.14-1.58)]. The odds of h-CHL [2.16 (1.59-2.95)], h-TG [1.21 (1.01-1.47)], e-LDL [1.42 (1.13-1.80)] and l-HDL [0.78 (0.65-0.93)] increased with hypertension. Diabetes mellitus doubled only the odds of h-TG [2.04(1.36-3.03)]. CONCLUSION: The prevalence of dyslipidaemia, particularly low HDL-C, is high among adult Nigerians.
AIM: The aim of this study was to determine the prevalence and predictors of dyslipidaemia in adults in Nigeria. METHODS: Using the WHO criteria, we determined dyslipidaemia using serum lipid levels of 3 211 adult Nigerians, aged at least 18 years, obtained between March 2017 and February 2018 from two communities (rural and urban) in a state from each of the six geopolitical zones of Nigeria. RESULTS: The overall prevalence of low high-density lipoprotein cholesterol (l-HDL), elevated low-density lipoprotein cholesterol (e-LDL), hypertriglyceridaemia (h-TG) and hypercholesterolaemia (h-CHL) were 72.5,13.6, 21.4 and 7.5%, respectively. The adjusted odds of h-CHL [odds ratio (95% confidence interval) 1.47 (1.10-1.95)], h-TG [1.89 (1.48-2.41)] and e-LDL [1.51 (1.03-2.15)] increased with obesity. Being a rural dweller increased the odds of h-TG [1.55 (1.29-1.85)], e-LDL [1.38 (1.10-1.73)] and l-HDL [1.34 (1.14-1.58)]. The odds of h-CHL [2.16 (1.59-2.95)], h-TG [1.21 (1.01-1.47)], e-LDL [1.42 (1.13-1.80)] and l-HDL [0.78 (0.65-0.93)] increased with hypertension. Diabetes mellitus doubled only the odds of h-TG [2.04(1.36-3.03)]. CONCLUSION: The prevalence of dyslipidaemia, particularly low HDL-C, is high among adult Nigerians.
Authors: G Kees Hovingh; Eric de Groot; Wim van der Steeg; S Matthijs Boekholdt; Barbara A Hutten; Jan Albert Kuivenhoven; John J P Kastelein Journal: Curr Opin Lipidol Date: 2005-04 Impact factor: 4.776
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Authors: Gershim Asiki; Georgina A V Murphy; Kathy Baisley; Rebecca N Nsubuga; Alex Karabarinde; Robert Newton; Janet Seeley; Elizabeth H Young; Anatoli Kamali; Manjinder S Sandhu Journal: PLoS One Date: 2015-05-14 Impact factor: 3.240
Authors: Azuka S Adeke; Babangida S Chori; Dinesh Neupane; James E Sharman; Augustine N Odili Journal: J Hum Hypertens Date: 2022-03-24 Impact factor: 3.012