Kirti Chaudhry 1 , Shruti Khatana 2 , Amanjot Kaur 1 , Shailendra Kumar 1 , P G Gigi 1 , G Aparna 1 Show Affiliations »
Abstract
TRIAL DESIGN: The study was designed as an open label randomized comparative parallel group design with a 1:1 allocation ratio. METHODS: All consecutive patients reporting for small biopsies (incisional or excisional) who gave written informed consent were included in the study between October 2018 and October 2019. They were randomized into two groups, Group A and Group B both receiving intervention in the form of 2.5% EMLA cream and 2% Lignocaine with 1:80,000 Adrenaline injection respectively, to anaesthetise tissue for small mucosal biopsies in the oral cavity. RESULTS: EMLA was found to be as effective as lignocaine infiltration with a completely painless application and higher satisfaction for overall comfort during procedure. The duration required to achieve anaesthesia was however more. A particular subgroup of pathology was found to be completely resistant to anaesthesia by EMLA. CONCLUSION: We recommend the use of EMLA as a sole anaesthetic in small mucosal biopsies and shavings in all patients. We suggest it as a higher and first line recommendation for anaesthesia in needle phobic patients and children. © The Association of Oral and Maxillofacial Surgeons of India 2020.
TRIAL DESIGN: The study was designed as an open label randomized comparative parallel group design with a 1:1 allocation ratio. METHODS: All consecutive patients reporting for small biopsies (incisional or excisional) who gave written informed consent were included in the study between October 2018 and October 2019. They were randomized into two groups, Group A and Group B both receiving intervention in the form of 2.5% EMLA cream and 2% Lignocaine with 1:80,000 Adrenaline injection respectively, to anaesthetise tissue for small mucosal biopsies in the oral cavity. RESULTS: EMLA was found to be as effective as lignocaine infiltration with a completely painless application and higher satisfaction for overall comfort during procedure. The duration required to achieve anaesthesia was however more. A particular subgroup of pathology was found to be completely resistant to anaesthesia by EMLA. CONCLUSION: We recommend the use of EMLA as a sole anaesthetic in small mucosal biopsies and shavings in all patients. We suggest it as a higher and first line recommendation for anaesthesia in needle phobic patients and children. © The Association of Oral and Maxillofacial Surgeons of India 2020.
Entities: Chemical
Keywords:
Anaesthesia; Biopsy; EMLA; Oral biopsy
Year: 2020
PMID： 34776695 PMCID： PMC8554955 DOI： 10.1007/s12663-020-01363-6
Source DB: PubMed Journal: J Maxillofac Oral Surg ISSN： 0972-8270