Literature DB >> 34776212

A mapping platform for mitotic crossover by single-cell multi-omics.

Peter Chovanec1, Yi Yin2.   

Abstract

Mitotic crossovers have the potential to cause large-scale genome rearrangements. Here, we describe high-throughput, single-cell, whole-genome sequencing methods for mapping crossovers genome-wide at scale. The methods are generalizable to various eukaryotes and to other end points requiring high-throughput, high-coverage single cell sequencing.
Copyright © 2021 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Genome instability; Homologous recombination; Linear amplification; Mitotic crossover; Mitotic recombination; Single-cell combinatorial indexing; Single-cell sequencing

Mesh：

Year:  2021        PMID： 34776212      PMCID： PMC8944907          DOI： 10.1016/bs.mie.2021.08.017

Source DB:  PubMed          Journal:  Methods Enzymol        ISSN： 0076-6879            Impact factor:   1.600


  38 in total

1.  breakpointR: an R/Bioconductor package to localize strand state changes in Strand-seq data.

Authors:  David Porubsky; Ashley D Sanders; Aaron Taudt; Maria Colomé-Tatché; Peter M Lansdorp; Victor Guryev
Journal:  Bioinformatics       Date:  2020-02-15       Impact factor: 6.937

2.  A global view of meiotic double-strand break end resection.

Authors:  Eleni P Mimitou; Shintaro Yamada; Scott Keeney
Journal:  Science       Date:  2017-01-06       Impact factor: 47.728

3.  DNA template strand sequencing of single-cells maps genomic rearrangements at high resolution.

Authors:  Ester Falconer; Mark Hills; Ulrike Naumann; Steven S S Poon; Elizabeth A Chavez; Ashley D Sanders; Yongjun Zhao; Martin Hirst; Peter M Lansdorp
Journal:  Nat Methods       Date:  2012-10-07       Impact factor: 28.547

4.  Characterization of systemic genomic instability in budding yeast.

Authors:  Nadia M V Sampaio; V P Ajith; Ruth A Watson; Lydia R Heasley; Parijat Chakraborty; Aline Rodrigues-Prause; Ewa P Malc; Piotr A Mieczkowski; Koodali T Nishant; Juan Lucas Argueso
Journal:  Proc Natl Acad Sci U S A       Date:  2020-10-26       Impact factor: 11.205

5.  Neuronal enhancers are hotspots for DNA single-strand break repair.

Authors:  Wei Wu; Sarah E Hill; William J Nathan; Jacob Paiano; Elsa Callen; Dongpeng Wang; Kenta Shinoda; Niek van Wietmarschen; Jennifer M Colón-Mercado; Dali Zong; Raffaella De Pace; Han-Yu Shih; Steve Coon; Maia Parsadanian; Raphael Pavani; Hana Hanzlikova; Solji Park; Seol Kyoung Jung; Peter J McHugh; Andres Canela; Chongyi Chen; Rafael Casellas; Keith W Caldecott; Michael E Ward; André Nussenzweig
Journal:  Nature       Date:  2021-03-25       Impact factor: 49.962

6.  Sensitive mapping of recombination hotspots using sequencing-based detection of ssDNA.

Authors:  Pavel P Khil; Fatima Smagulova; Kevin M Brick; R Daniel Camerini-Otero; Galina V Petukhova
Journal:  Genome Res       Date:  2012-02-24       Impact factor: 9.043

7.  Genome-wide high-resolution mapping of UV-induced mitotic recombination events in Saccharomyces cerevisiae.

Authors:  Yi Yin; Thomas D Petes
Journal:  PLoS Genet       Date:  2013-10-31       Impact factor: 5.917

8.  Genome-destabilizing effects associated with top1 loss or accumulation of top1 cleavage complexes in yeast.

Authors:  Sabrina L Andersen; Roketa S Sloan; Thomas D Petes; Sue Jinks-Robertson
Journal:  PLoS Genet       Date:  2015-04-01       Impact factor: 5.917

9.  The repertoire of mutational signatures in human cancer.

Authors:  Ludmil B Alexandrov; Jaegil Kim; Gad Getz; Steven G Rozen; Michael R Stratton; Nicholas J Haradhvala; Mi Ni Huang; Alvin Wei Tian Ng; Yang Wu; Arnoud Boot; Kyle R Covington; Dmitry A Gordenin; Erik N Bergstrom; S M Ashiqul Islam; Nuria Lopez-Bigas; Leszek J Klimczak; John R McPherson; Sandro Morganella; Radhakrishnan Sabarinathan; David A Wheeler; Ville Mustonen
Journal:  Nature       Date:  2020-02-05       Impact factor: 49.962

10.  BLM helicase suppresses recombination at G-quadruplex motifs in transcribed genes.

Authors:  Niek van Wietmarschen; Sarra Merzouk; Nancy Halsema; Diana C J Spierings; Victor Guryev; Peter M Lansdorp
Journal:  Nat Commun       Date:  2018-01-18       Impact factor: 14.919
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.