Literature DB >> 34767489

Clumpy artifacts can be differentiated from tophi with DECT: comparison between gout-free and gouty patients.

Dong Han Shin1, You Seon Song2, Yunjung Choi3,4, Wan-Hee Yoo3,4, Florian Kummel5, Eun Hae Park1,4.   

Abstract

OBJECTIVES: To accurately differentiate clumpy artifacts from tophi with foot and ankle DECT. METHODS AND MATERIALS: In session 1, 108 clumpy artifacts from 35 patients and 130 tophi images from 25 patients were analyzed. Reviewers classified green pixelation according to anatomic location, shape (linear, stippled, angular, oval), and height and width ratio. In session 2, green pixelation confined to the tendon was evaluated (shape, height and width ratio, occupied area in the tendon, accompanied peritendinous green pixelation).
RESULTS: In session 1, while tophi were noted at various locations, almost all clumpy artifacts were located at the tendon (99%, p < 0.0001). Most clumpy artifacts were linear, stippled, and wide, while most tophi were angular and oval (p < 0.05). In session 2, the shape of green pixelation from clumpy artifacts and tophi was significantly different (p < 0.0001) and most clumpy artifacts occupied less than 50% of the tendon (p = 0.02), and most tophi were accompanied by peritendinous green pixelation (p < 0.0001). Univariant logistic regression showed that tophi were significantly correlated with peritendinous deposits, angular and oval shape, and more than 50% of the tendon (p < 0.05).
CONCLUSION: Clumpy artifacts can be differentiated from tophi in DECT. Clumpy artifacts typically are located in the tendon with a linear or stippled shape, wide, and less than 50% of a tendon's cross-section. Tophi, on the other hand, typically are oval, larger than 50% of the tendon's cross-section, and associated with adjacent peritendinous green pixelation. ADVANCES IN KNOWLEDGE: Clumpy artifacts can be differentiated from tophi in image findings by their location and shape.

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Year:  2021        PMID: 34767489      PMCID: PMC8722253          DOI: 10.1259/bjr.20210990

Source DB:  PubMed          Journal:  Br J Radiol        ISSN: 0007-1285            Impact factor:   3.039


  28 in total

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2.  Dual Energy CT in Clinical Practice.

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3.  The British Society for Rheumatology Guideline for the Management of Gout.

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4.  Urate crystal deposition in asymptomatic hyperuricaemia and symptomatic gout: a dual energy CT study.

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5.  Quality control of the laboratory diagnosis of gout by synovial fluid microscopy.

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Review 7.  Clinical utility of dual-energy CT for evaluation of tophaceous gout.

Authors:  Madhura A Desai; Jeffrey J Peterson; Hillary Warren Garner; Mark J Kransdorf
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9.  Tendon involvement in the feet of patients with gout: a dual-energy CT study.

Authors:  Nicola Dalbeth; Ramanamma Kalluru; Opetaia Aati; Anne Horne; Anthony J Doyle; Fiona M McQueen
Journal:  Ann Rheum Dis       Date:  2013-01-19       Impact factor: 19.103

Review 10.  The Utility of Dual Energy Computed Tomography in Musculoskeletal Imaging.

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