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Literature DB >> 3476350

Disequilibrium pattern analysis. II. Application to Danish HLA A and B locus data.

Abstract

Disequilibrium pattern analysis, a general method for analyzing evolutionary events acting on pairs of tightly linked polymorphic loci, is applied to a large sample of Danish individuals typed for A and B loci of the HLA (human leukocyte antigen) system. Cases of selection on particular haplotypes are revealed from patterns of linkage disequilibrium among the HLA haplotypes. These patterns cannot be explained by either population admixture or random genetic drift. Six haplotypes out of the total array of 273 haplotypes have been identified which show in varying extents the patterns indicating selection.

Entities: Gene Species

Mesh：

Substances：

Year: 1987 PMID： 3476350 PMCID： PMC1203176

Source DB: PubMed Journal: Genetics ISSN： 0016-6731 Impact factor: 4.562

14 in total

1. Infectious diseases in primitive societies.

Authors: F L Black
Journal: Science Date: 1975-02-14 Impact factor: 47.728

Review 2. Class I genes and molecules: an update.

Authors: A M Lew; E P Lillehoj; E P Cowan; W L Maloy; M R van Schravendijk; J E Coligan
Journal: Immunology Date: 1986-01 Impact factor: 7.397

3. Synthetic maps of human gene frequencies in Europeans.

Authors: P Menozzi; A Piazza; L Cavalli-Sforza
Journal: Science Date: 1978-09-01 Impact factor: 47.728

4. The effect of population subdivision on two loci without selection.

Authors: M W Feldman; F B Christiansen
Journal: Genet Res Date: 1974-10 Impact factor: 1.588

5. Studies on African Pygmies. IV. A comparative study of the HL-A polymorphism in the Babinga Pygmies and other African and Caucasian populations.

Authors: J G Bodmer; W F Bodmer
Journal: Am J Hum Genet Date: 1970-07 Impact factor: 11.025

6. Maintenance of histocompatibility polymorphisms.

Authors: F E Warburton
Journal: Heredity (Edinb) Date: 1968-02 Impact factor: 3.821

Review 7. Genes of the major histocompatibility complex of the mouse.

Authors: L Hood; M Steinmetz; B Malissen
Journal: Annu Rev Immunol Date: 1983 Impact factor: 28.527

8. A review of theoretical aspects of HLA and disease associations.

Authors: G Thomson
Journal: Theor Popul Biol Date: 1981-10 Impact factor: 1.570

9. HLA--A, B haplotype frequencies in 5,202 unrelated Danes by a maximum-likelihood method of gene counting.

Authors: H E Hansen; S O Larsen; L P Ryder; L S Nielsen
Journal: Tissue Antigens Date: 1979-02

10. Control of mating preferences in mice by genes in the major histocompatibility complex.

Authors: K Yamazaki; E A Boyse; V Miké; H T Thaler; B J Mathieson; J Abbott; J Boyse; Z A Zayas; L Thomas
Journal: J Exp Med Date: 1976-11-02 Impact factor: 14.307

14 in total

1. Distribution of nonrandom associations between pairs of protein loci along the third chromosome of Drosophila melanogaster.

Authors: Carlos Zapata; Concepción Núñez; Teresa Velasco
Journal: Genetics Date: 2002-08 Impact factor: 4.562

Disequilibrium pattern analysis. II. Application to Danish HLA A and B locus data.

1. Infectious diseases in primitive societies.

Review 2. Class I genes and molecules: an update.

3. Synthetic maps of human gene frequencies in Europeans.

4. The effect of population subdivision on two loci without selection.

5. Studies on African Pygmies. IV. A comparative study of the HL-A polymorphism in the Babinga Pygmies and other African and Caucasian populations.

6. Maintenance of histocompatibility polymorphisms.

Review 7. Genes of the major histocompatibility complex of the mouse.

8. A review of theoretical aspects of HLA and disease associations.

9. HLA--A, B haplotype frequencies in 5,202 unrelated Danes by a maximum-likelihood method of gene counting.

10. Control of mating preferences in mice by genes in the major histocompatibility complex.

1. Distribution of nonrandom associations between pairs of protein loci along the third chromosome of Drosophila melanogaster.

2. Major histocompatibility complex differentiation in Sacramento River chinook salmon.

3. Signatures of demographic history and natural selection in the human major histocompatibility complex Loci.

4. Gametic equilibrium between 24 polymorphic markers.

5. The extent, mechanism, and consequences of genetic variation, for recombination rate.

6. Genetic analysis of HLA in the U.S. Schmiedenleut Hutterites.

7. HLA polymorphism in the Havasupai: evidence for balancing selection.

8. Discordant patterns of linkage disequilibrium of the peptide-transporter loci within the HLA class II region.

9. HLA class II linkage disequilibrium and haplotype evolution in the Cayapa Indians of Ecuador.

10. Constrained disequilibrium values and hitchhiking in a three-locus system.