Literature DB >> 34762846

Melatonin Prescribing in Assisted Living.

Punita Peketi1, Sheryl Zimmerman2, Stephanie Palmertree3, Christopher J Wretman4, John S Preisser5, Philip D Sloane6.   

Abstract

OBJECTIVES: Aging is associated with sleep problems, which are common among assisted living (AL) residents. More than 40% of residents have insomnia, and almost 70% have a sleep disturbance of some kind. Melatonin to treat sleep disorders has become common among older adults, but its use in AL is unknown, which is concerning because melatonin may have side effects and interfere with other medications. The purpose of this study was to determine the prevalence and correlates of melatonin prescribing in AL, to inform whether changes in care may be indicated.
DESIGN: Cross-sectional chart abstracts and interviews. SETTINGS AND PARTICIPANTS: Data were collected in 250 randomly selected AL communities among 5777 residents across 7 states in the United States and weighted to an estimated 4043 communities and 152,719 residents.
METHODS: Charts of residents were abstracted, and AL administrators and health care supervisors were interviewed to obtain information related to case-mix, staffing, and attitudes regarding psychoactive medications. Weighted analyses primarily examined the association of melatonin prescribing with community- and resident-level characteristics.
RESULTS: Melatonin was prescribed in 82% of communities, more commonly in those that had a registered nurse or licensed practical nurse on site (+7%, P = .027), and whose health care supervisor was more favorable toward nonpharmacologic practices (+18%, P = .010). On average, 9% of residents were prescribed melatonin, with prescriptions being more common among those diagnosed with dementia (+24%, P = .004); a psychiatric disorder, especially an anxiety disorder (+43%, P = .007); having behavioral expressions; and taking other psychotropics. Coprescribing was common, especially with antidepressants (OR 2.64, 95% CI 1.99, 3.48; P < .001). CONCLUSIONS AND IMPLICATIONS: This study is the first to examine melatonin prescribing in AL, and finds it to be common. Such use may be appropriate if it is as a more suitable replacement for hypnotics. The fact that use varies by organizational characteristics suggests practices may be modifiable. Research examining benefits and side effects of melatonin, overall and in relation to other medications, is indicated to promote better care for AL residents.
Copyright © 2021 AMDA – The Society for Post-Acute and Long-Term Care Medicine. Published by Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Assisted living; medication; prescribing

Mesh:

Substances:

Year:  2021        PMID: 34762846      PMCID: PMC9097337          DOI: 10.1016/j.jamda.2021.10.005

Source DB:  PubMed          Journal:  J Am Med Dir Assoc        ISSN: 1525-8610            Impact factor:   7.802


  30 in total

1.  How good is assisted living? Findings and implications from an outcomes study.

Authors:  Sheryl Zimmerman; Philip D Sloane; J Kevin Eckert; Ann L Gruber-Baldini; Leslie A Morgan; J Richard Hebel; Jay Magaziner; Sally C Stearns; Cory K Chen
Journal:  J Gerontol B Psychol Sci Soc Sci       Date:  2005-07       Impact factor: 4.077

2.  A pharmacological dose of melatonin increases PRL levels in males without altering those of GH, LH, FSH, TSH, testosterone or cortisol.

Authors:  F Waldhauser; H R Lieberman; H J Lynch; M Waldhauser; K Herkner; H Frisch; H Vierhapper; W Waldhäusl; M Schemper; R J Wurtman
Journal:  Neuroendocrinology       Date:  1987-08       Impact factor: 4.914

3.  Prescribing of psychotropic drugs and indicators for use in residential aged care and residents with dementia.

Authors:  R E Brimelow; J A Wollin; G J Byrne; N N Dissanayaka
Journal:  Int Psychogeriatr       Date:  2018-11-20       Impact factor: 3.878

Review 4.  Adverse Effects of Psychotropic Medications on Sleep.

Authors:  Karl Doghramji; William C Jangro
Journal:  Psychiatr Clin North Am       Date:  2016-06-24

5.  Sleep disturbances in the elderly residing in assisted living: findings from the Maryland Assisted Living Study.

Authors:  Vani Rao; Jennifer R Spiro; Quincy M Samus; Adam Rosenblatt; Cynthia Steele; Alva Baker; Michael Harper; Jason Brandt; Lawrence Mayer; Peter V Rabins; Constantine G Lyketsos
Journal:  Int J Geriatr Psychiatry       Date:  2005-10       Impact factor: 3.485

6.  Trends in the use of complementary health approaches among adults: United States, 2002-2012.

Authors:  Tainya C Clarke; Lindsey I Black; Barbara J Stussman; Patricia M Barnes; Richard L Nahin
Journal:  Natl Health Stat Report       Date:  2015-02-10

Review 7.  Melatonin: clinical relevance.

Authors:  Russel J Reiter
Journal:  Best Pract Res Clin Endocrinol Metab       Date:  2003-06       Impact factor: 4.690

8.  Effect of bright light and melatonin on cognitive and noncognitive function in elderly residents of group care facilities: a randomized controlled trial.

Authors:  Rixt F Riemersma-van der Lek; Dick F Swaab; Jos Twisk; Elly M Hol; Witte J G Hoogendijk; Eus J W Van Someren
Journal:  JAMA       Date:  2008-06-11       Impact factor: 56.272

9.  Inappropriate long-term use of antipsychotic drugs is common among people with dementia living in specialized care units.

Authors:  Maria Gustafsson; Stig Karlsson; Hugo Lövheim
Journal:  BMC Pharmacol Toxicol       Date:  2013-02-08       Impact factor: 2.483

10.  A Review Exploring the Relationship Between Nursing Home Staffing and Antipsychotic Medication Use.

Authors:  T Joseph Mattingly
Journal:  Neurol Ther       Date:  2015-09-02
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  2 in total

Review 1.  Melatonin's Benefits and Risks as a Therapy for Sleep Disturbances in the Elderly: Current Insights.

Authors:  Daniel P Cardinali; Gregory M Brown; Seithikurippu R Pandi-Perumal
Journal:  Nat Sci Sleep       Date:  2022-10-14

2.  Dementia and COVID-19 infection control in assisted living in seven states.

Authors:  Sheryl Zimmerman; Philip D Sloane; Johanna Silbersack Hickey; Christopher J Wretman; Selen P Gizlice; Kali S Thomas; Paula Carder; John S Preisser
Journal:  J Am Geriatr Soc       Date:  2022-06-14       Impact factor: 7.538

  2 in total

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