Literature DB >> 3476150

A new specific chromosomal rearrangement, t(8;16) (p11;p13), in acute monocytic leukaemia.

S Heim, G C Avanzi, R Billström, U Kristoffersson, N Mandahl, A N Bekassy, S Garwicz, T Wiebe, L Pegoraro, M Falda.   

Abstract

The translocation t(8;16) (p11;p13) was found as the sole deviation from the normal karyotype in three patients with acute monocytic leukaemia. The bone marrow morphology was strikingly similar in the two cases where smears were available for re-evaluation: the leukaemic cells showed signs of differentiation, and active erythrophagocytosis was a particularly conspicuous feature. We suggest that t(8;16) (p11;p13) represents a new consistent abnormality in acute monocytic leukaemia, specifically associated with the differentiated subtype (M5b) and with pronounced phagocytic activity by the leukaemic monocytes.

Entities:  

Mesh：

Year:  1987        PMID： 3476150     DOI： 10.1111/j.1365-2141.1987.tb06917.x

Source DB:  PubMed          Journal:  Br J Haematol        ISSN： 0007-1048            Impact factor:   6.998


  7 in total

1.  Translocation t(8;16)(p11;p13) in neonatal acute monocytic leukaemia.

Authors:  T Hanada; I Ono; Y Minosaki; N Moriyama; S Nakahara; A Ohtsu
Journal:  Eur J Pediatr       Date:  1991-03       Impact factor: 3.183

Review 2.  Contribution of immunophenotypic and genotypic analyses to the diagnosis of acute leukemia.

Authors:  R Stasi; C G Taylor; A Venditti; G Del Poeta; G Aronica; C Bastianelli; M D Simone; F Buccisano; M C Cox; A Bruno
Journal:  Ann Hematol       Date:  1995-07       Impact factor: 3.673

3.  Pediatric acute myeloid leukemia with t(8;16)(p11;p13), a distinct clinical and biological entity: a collaborative study by the International-Berlin-Frankfurt-Munster AML-study group.

Authors:  Eva A Coenen; C Michel Zwaan; Dirk Reinhardt; Christine J Harrison; Oskar A Haas; Valerie de Haas; Vladimir Mihál; Barbara De Moerloose; Marta Jeison; Jeffrey E Rubnitz; Daisuke Tomizawa; Donna Johnston; Todd A Alonzo; Henrik Hasle; Anne Auvrignon; Michael Dworzak; Andrea Pession; Vincent H J van der Velden; John Swansbury; Kit-fai Wong; Kiminori Terui; Sureyya Savasan; Mark Winstanley; Goda Vaitkeviciene; Martin Zimmermann; Rob Pieters; Marry M van den Heuvel-Eibrink
Journal:  Blood       Date:  2013-08-23       Impact factor: 22.113

4.  Comparison between karyotyping-FISH-reverse transcription PCR and RNA-sequencing-fusion gene identification programs in the detection of KAT6A-CREBBP in acute myeloid leukemia.

Authors:  Ioannis Panagopoulos; Synne Torkildsen; Ludmila Gorunova; Anne Tierens; Geir E Tjønnfjord; Sverre Heim
Journal:  PLoS One       Date:  2014-05-05       Impact factor: 3.240

5.  MYST3/CREBBP Rearranged Acute Myeloid Leukemia after Adjuvant Chemotherapy for Breast Cancer.

Authors:  Arjun Gupta; Mrinal M Patnaik; Harris V Naina
Journal:  Case Rep Oncol Med       Date:  2014-12-08

6.  A new gene, BCM, on chromosome 16 is fused to the interleukin 2 gene by a t(4;16)(q26;p13) translocation in a malignant T cell lymphoma.

Authors:  Y Laâbi; M P Gras; F Carbonnel; J C Brouet; R Berger; C J Larsen; A Tsapis
Journal:  EMBO J       Date:  1992-11       Impact factor: 11.598

7.  [Acute myeloid leukemia and translocation (8; 16) (p11; p13), the first Moroccan case of a distinct clinical-biological entity].

Authors:  Adiba Bakkali; Mouna Lemchaheb; Nezha Had; Hind Dehbi; Said Benchekroun; Asma Quessar
Journal:  Pan Afr Med J       Date:  2015-06-23
  7 in total

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