Literature DB >> 34760839

Oncological Safety, Surgical Outcome, and Patient Satisfaction of Oncoplastic Breast-Conserving Surgery With Contralateral Balancing Reduction Mammoplasty.

Hannah St Denis-Katz1, Bahareh B Ghaedi2, Aisling Fitzpatrick1, Jing Zhang3.   

Abstract

INTRODUCTION: Oncoplastic breast-conserving surgery (OBCS) is considered a cornerstone in the management of locally invasive breast cancer. We evaluated patient-reported outcomes of OBCS with contralateral balancing breast reduction mammoplasty and reviewed its oncologic outcomes and complications.
METHODS: This is mixed method study design using retrospective chart review and prospective cohort study. Patient demographics were reviewed. Outcome measures included clinicopathologic characteristics, complications, margin status, local recurrence, tumor histopathologies, duration of follow-up, patient satisfaction, self-esteem, event-related stress, and quality of life.
RESULTS: A total of 48 patients were included in this study. Complete excision with negative margins was obtained in 42 (87.5%) patients, positive margins in 6 (12.5%) patients, all who had re-excision with repeat lumpectomy. Thirteen patients developed minor complications, defined as being managed as an outpatient. No patients developed major complications requiring inpatient admission. These complications did not delay commencement of chemotherapy or radiotherapy. Postsurgery BREAST-QTM26 scores demonstrated no statistical difference in satisfaction with breasts, nipples, and sexual well-being. There was high satisfaction with overall outcome with average score of 80.8%. For the Rosenberg self-esteem scale, the results were similar for 3- and 12-month post-operative indicating maintenance of normal self-esteem post-operatively. The Impact of Events Scale showed statistically significant difference at 12-month post-operative (25.1) when compared with preoperative scores indicating that patients had lower event-related stress. There was no significant change in Hospital Anxiety and Depression Scale.
CONCLUSION: Our study has shown that the patient who undergo OBCS have high patient-reported outcomes with acceptable oncologic outcomes and complication rates.
© 2020 The Author(s).

Entities:  

Keywords:  breast cancer; breast reconstruction; breast-conserving surgery; oncoplastic breast-conserving surgery; oncoplastic reconstruction

Year:  2020        PMID: 34760839      PMCID: PMC8573638          DOI: 10.1177/2292550320969645

Source DB:  PubMed          Journal:  Plast Surg (Oakv)        ISSN: 2292-5503            Impact factor:   0.947


  33 in total

Review 1.  Outcomes After Oncoplastic Breast-Conserving Surgery in Breast Cancer Patients: A Systematic Literature Review.

Authors:  Lucy De La Cruz; Stephanie A Blankenship; Abhishek Chatterjee; Rula Geha; Nadia Nocera; Brian J Czerniecki; Julia Tchou; Carla S Fisher
Journal:  Ann Surg Oncol       Date:  2016-06-29       Impact factor: 5.344

2.  Mastectomy versus breast-conserving therapy in the treatment of stage I and II carcinoma of the breast: a randomized trial at the National Cancer Institute.

Authors:  A S Lichter; M E Lippman; D N Danforth; T d'Angelo; S M Steinberg; E deMoss; H D MacDonald; C M Reichert; M Merino; S M Swain
Journal:  J Clin Oncol       Date:  1992-06       Impact factor: 44.544

3.  Evaluation of Surgical Outcomes of Oncoplasty Breast Surgery in Locally Advanced Breast Cancer and Comparison with Conventional Breast Conservation Surgery.

Authors:  Ashutosh Chauhan; Mala Mathur Sharma; Kishore Kumar
Journal:  Indian J Surg Oncol       Date:  2016-08-26

4.  Long-term results of a randomized trial comparing breast-conserving therapy with mastectomy: European Organization for Research and Treatment of Cancer 10801 trial.

Authors:  J A van Dongen; A C Voogd; I S Fentiman; C Legrand; R J Sylvester; D Tong; E van der Schueren; P A Helle; K van Zijl; H Bartelink
Journal:  J Natl Cancer Inst       Date:  2000-07-19       Impact factor: 13.506

5.  Outcome of oncoplastic breast surgery in 90 prospective patients.

Authors:  Tuomo J Meretoja; Catarina Svarvar; Tiina A Jahkola
Journal:  Am J Surg       Date:  2010-06-22       Impact factor: 2.565

6.  Oncological results of oncoplastic breast-conserving surgery: Long term follow-up of a large series at a single institution: A matched-cohort analysis.

Authors:  F De Lorenzi; G Hubner; N Rotmensz; V Bagnardi; P Loschi; P Maisonneuve; M Venturino; R Orecchia; V Galimberti; P Veronesi; M Rietjens
Journal:  Eur J Surg Oncol       Date:  2015-09-08       Impact factor: 4.424

Review 7.  A systematic review of oncoplastic breast-conserving surgery: current weaknesses and future prospects.

Authors:  Max H Haloua; Nicole M A Krekel; Henri A H Winters; Derek H F Rietveld; Sybren Meijer; Frank W Bloemers; Monique P van den Tol
Journal:  Ann Surg       Date:  2013-04       Impact factor: 12.969

8.  Development of a new patient-reported outcome measure for breast surgery: the BREAST-Q.

Authors:  Andrea L Pusic; Anne F Klassen; Amie M Scott; Jennifer A Klok; Peter G Cordeiro; Stefan J Cano
Journal:  Plast Reconstr Surg       Date:  2009-08       Impact factor: 4.730

9.  Impact of Event Scale: a measure of subjective stress.

Authors:  M Horowitz; N Wilner; W Alvarez
Journal:  Psychosom Med       Date:  1979-05       Impact factor: 4.312

10.  Twenty-year follow-up of a randomized study comparing breast-conserving surgery with radical mastectomy for early breast cancer.

Authors:  Umberto Veronesi; Natale Cascinelli; Luigi Mariani; Marco Greco; Roberto Saccozzi; Alberto Luini; Marisel Aguilar; Ettore Marubini
Journal:  N Engl J Med       Date:  2002-10-17       Impact factor: 91.245

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  2 in total

1.  Patient-level costs of staged unilateral versus immediate bilateral symmetrization mammoplasty in breast-conserving surgery.

Authors:  Yasmin Grant; Paul T R Thiruchelvam; Lana Kovacevic; Elias Mossialos; Ragheed Al-Mufti; Katy Hogben; Dimitri J Hadjiminas; Daniel R Leff
Journal:  BJS Open       Date:  2022-05-02

Review 2.  Breast Radiotherapy after Oncoplastic Surgery-A Multidisciplinary Approach.

Authors:  Gabrielle Metz; Kylie Snook; Samriti Sood; Sally Baron-Hay; Andrew Spillane; Gillian Lamoury; Susan Carroll
Journal:  Cancers (Basel)       Date:  2022-03-25       Impact factor: 6.639

  2 in total

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