| Literature DB >> 34757768 |
Jackson T Wright1, Paul K Whelton2, Karen C Johnson3, Joni K Snyder4, David M Reboussin5, William C Cushman3, Jeff D Williamson6, Nicholas M Pajewski5, Alfred K Cheung7, Cora E Lewis8, Suzanne Oparil9, Michael V Rocco10, Srinivasan Beddhu7, Lawrence J Fine4, Jeffrey A Cutler4, Walter T Ambrosius5, Mahboob Rahman1, Carolyn H Still11, Zhengyi Chen12, Curtis Tatsuoka12.
Abstract
The SPRINT (Systolic Blood Pressure Intervention Trial) results have influenced clinical practice but have also generated discussion regarding the validity, generalizability, and importance of the findings. Following the SPRINT primary results manuscript in 2015, additional results and analyses of the data have addressed these concerns. The primary objective of this article is to respond to key questions that have been raised.Entities:
Keywords: blood pressure; cardiovascular disease; controlled clinical trial; heart failure; hypertension; myocardial infarction
Mesh:
Substances:
Year: 2021 PMID: 34757768 PMCID: PMC8824314 DOI: 10.1161/HYPERTENSIONAHA.121.17682
Source DB: PubMed Journal: Hypertension ISSN: 0194-911X Impact factor: 10.190