Literature DB >> 3474913

Search for genetic variation in the blood of Norwegian dairy goats reveals a new polymorphism at the Hb beta A locus.

M Braend, E M Tucker, S W Clarke.   

Abstract

A total of 150 blood samples tested for serum albumin and transferrin and for red cell carbonic anhydrase, phosphoglucomutase, phosphogluconate dehydrogenase, phosphohexose isomerase, nucleoside phosphorylase, acid phosphatase, 'X'-protein and potassium concentration only showed variation at the 'X' protein and nucleoside phosphorylase loci. Isoelectric focusing over pH range 6-8 showed 145 samples to be of haemoglobin type A and 5 type AD. The haemoglobin A type was resolved into further types by separation over pH 6.9-7.5 in Immobiline polyacrylamide gels. A 2- or 4-band pattern was present in 136 of the samples; a genetic hypothesis based on four or more different haemoglobin A variants is proposed. 14 samples had a 3-, 5- or 6-band pattern. It is assumed that these are heterozygous for a variant of the II alpha gene.

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Year:  1987        PMID: 3474913     DOI: 10.1111/j.1365-2052.1987.tb00746.x

Source DB:  PubMed          Journal:  Anim Genet        ISSN: 0268-9146            Impact factor:   3.169


  1 in total

1.  Hemoglobin types in Saanen goats and Barbary sheep: genetic and comparative aspects.

Authors:  M Braend; E M Tucker
Journal:  Biochem Genet       Date:  1988-08       Impact factor: 1.890

  1 in total

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