Literature DB >> 34747437

The impact of dissection membrane motility on mid-term aortic remodelling after thoracic endovascular repair.

Mario Lescan1, Migdat Mustafi1, Viktoria Wilhelm2, Marius Keller2, Christian Schlensak1, Peter Rosenberger2, Harry Magunia2.   

Abstract

OBJECTIVES: The aim of this study was to assess preoperative dissection flap motility and to evaluate its impact on the aortic remodelling and the development of distal stent-induced new entry after thoracic endovascular aneurysm repair (TEVAR)/frozen elephant trunk (FET).
METHODS: Patients with primary or residual type B dissections were included in a retrospective study with transoesophageal echocardiography analysis of the preoperative dissection flap motility assessed by the true lumen (TL) strain. Three-dimensional computing tomography centreline reconstructions before TEVAR/FET and during the follow-up were conducted to measure aortic remodelling: false lumen thrombosis, TL expansion and aortic diameters at 10 and 20 cm downstream the left subclavian artery, at the coeliac trunk and in the infrarenal aorta. All continuous variables are reported as median with first and third quartiles.
RESULTS: Fifty-six consecutive patients were treated with TEVAR (n = 45) or FET (n = 11) in the acute (n = 16), subacute (n = 16) and chronic (n = 24) dissection phase. At a median follow-up of 6 (3-12) months, they showed a favourable TL expansion in the descending aorta, significantly higher in the acute [+9 mm (5-12); P < 0.001] and subacute groups [+5 mm (3-8); P = 0.039] than in the chronic group [+2 mm (0-5)]. The dissection flap motility parameter TL strain was superior in the acute (P = 0.006) and subacute (P = 0.035) groups in comparison to the chronic group. The motile flap [TL strain >22.5% (median)] was associated with a higher TL expansion rate in the thoracic aorta (P = 0.009) and a comparable distal stent-induced new entry incidence (overall: 16%) in comparison to the immobile flap (P = 0.89).
CONCLUSIONS: The intraoperative assessment and the inclusion of the dissection flap motility parameters in the decision-making during TEVAR/FET may refine the distal endograft sizing for an improved remodelling of the TL.
© The Author(s) 2021. Published by Oxford University Press on behalf of the European Association for Cardio-Thoracic Surgery. All rights reserved.

Entities:  

Keywords:  Aorta; Aortic remodelling; Dissection; Echocardiography; Thoracic endograft Thoracic endovascular aneurysm repair

Mesh:

Year:  2022        PMID: 34747437     DOI: 10.1093/ejcts/ezab444

Source DB:  PubMed          Journal:  Eur J Cardiothorac Surg        ISSN: 1010-7940            Impact factor:   4.191


  1 in total

1.  Time-dependent mechanical behaviour of the aortic chronic dissection flap.

Authors:  Phakakorn Panpho; Ying Yang; Hannah A Davies; Omar Nawaytou; Amer Harky; Francesco Torella; Mark Field; Jillian Madine; Riaz Akhtar
Journal:  Interact Cardiovasc Thorac Surg       Date:  2022-05-02
  1 in total

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