Aviane Auguste1, Samuel Gathere2, Paulo S Pinheiro3, Clement Adebamowo4, Adeola Akintola5, Kellie Alleyne-Mike6, Simon G Anderson7, Kimlin Ashing8, Fred Kwame Awittor9, Baffour Awuah10, Bernard Bhakkan11, Jacqueline Deloumeaux12, Maira du Plessis13, Ima-Obong A Ekanem14, Uwemedimbuk Ekanem15, Emmanuel Ezeome16, Nkese Felix17, Andrew K Gachii18, Stanie Gaete19, Tracey Gibson20, Robert Hage13, Sharon Harrison21, Festus Igbinoba22, Kufre Iseh23, Evans Kiptanui24, Ann Korir2, Heather-Dawn Lawson-Myers25, Adana Llanos26, Daniele Luce27, Dawn McNaughton20, Michael Odutola28, Abidemi Omonisi29, Theresa Otu30, Jessica Peruvien31, Nasiru Raheem32, Veronica Roach33, Natasha Sobers7, Nguundja Uamburu34, Camille Ragin21. 1. Guadeloupe Cancer Registry, University Hospital of Guadeloupe, Pointe-à-Pitre, Guadeloupe, France; African Caribbean Cancer Consortium USA. Electronic address: aviane_auguste@hotmail.com. 2. The National Cancer Registry, Kenya Medical Research Institute, Nairobi, Kenya; African Caribbean Cancer Consortium USA. 3. University of Miami, Sylvester Comprehensive Cancer Center, FL, USA; African Caribbean Cancer Consortium USA. 4. Department of Epidemiology and Public Health and the Institute of Human Virology, The Marlene and Stewart Greenebaum Comprehensive Cancer Centre, University of Maryland School of Medicine, Baltimore, MD, USA; Center for Bioethics and Research, Ibadan, Nigeria; Nigerian National System of Cancer Registries, Federal Ministry of Health, Abuja, Nigeria. 5. Center for Bioethics and Research, Ibadan, Nigeria; Nigerian National System of Cancer Registries, Federal Ministry of Health, Abuja, Nigeria. 6. Cancer Centre of Trinidad and Tobago, St. James, Trinidad and Tobago; African Caribbean Cancer Consortium USA. 7. Barbados National Registry, The George Alleyne Chronic Disease Research Centre, Caribbean Institute for Health Research, University of the West Indies, Cave Hill, Barbados; African Caribbean Cancer Consortium USA. 8. City of Hope Cancer Center, Duarte, CA, USA; African Caribbean Cancer Consortium USA. 9. Kumasi Cancer Registry, Komfo Anokye Teaching Hospital, Kumasi, Ghana. 10. Kumasi Cancer Registry, Komfo Anokye Teaching Hospital, Kumasi, Ghana; African Caribbean Cancer Consortium USA. 11. Guadeloupe Cancer Registry, University Hospital of Guadeloupe, Pointe-à-Pitre, Guadeloupe, France; African Caribbean Cancer Consortium USA. 12. Guadeloupe Cancer Registry, University Hospital of Guadeloupe, Pointe-à-Pitre, Guadeloupe, France; Biological Resource Center Karubiotec™, BRIF n° KARUBIOTEC-GUA-00971, Pointe-à-Pitre, Guadeloupe; African Caribbean Cancer Consortium USA. 13. Department of Anatomical Sciences, St Georges University, Grenada, West Indies; African Caribbean Cancer Consortium USA. 14. Nigerian National System of Cancer Registries, Federal Ministry of Health, Abuja, Nigeria; Calabar Cancer Registry, Department of Pathology, College of Medical Sciences, University of Calabar and Teaching Hospital, Calabar, Nigeria. 15. Nigerian National System of Cancer Registries, Federal Ministry of Health, Abuja, Nigeria; Department of Community Health, Faculty of Clinical Sciences, College of Health Sciences, University of Uyo/University of Uyo Teaching Hospital, Uyo, Nigeria. 16. Nigerian National System of Cancer Registries, Federal Ministry of Health, Abuja, Nigeria; Enugu Cancer Registry, University of Nigeria Teaching Hospital, Enugu, Nigeria. 17. Dr. Elizabeth Quamina Cancer Registry, the National Cancer Registry of Trinidad and Tobago, Mount Hope, Trinidad and Tobago. 18. Department of Lab Medicine, Kenyatta National Hospital, Nairobi, Kenya; African Caribbean Cancer Consortium USA. 19. Biological Resource Center Karubiotec™, BRIF n° KARUBIOTEC-GUA-00971, Pointe-à-Pitre, Guadeloupe; African Caribbean Cancer Consortium USA. 20. Jamaica Cancer Registry, Department of Pathology, University of the West Indies, Kingston, Jamaica; African Caribbean Cancer Consortium USA. 21. Cancer Prevention and Control Program, Fox Chase Cancer Center, Philadelphia, PA, USA; African Caribbean Cancer Consortium USA. 22. Nigerian National System of Cancer Registries, Federal Ministry of Health, Abuja, Nigeria; National Hospital Abuja, Abuja, Nigeria. 23. Nigerian National System of Cancer Registries, Federal Ministry of Health, Abuja, Nigeria; Department of Otorhinolaryngology/Head &Neck Surgery, Faculty of Clinical sciences, Usmanu Danfodiyo University/Usmanu Danfodiyo University Teaching Hospital, Sokoto, Nigeria; Population Based Cancer Registry, Usmanu Danfodiyo University Teaching Hospital, Sokoto, Nigeria. 24. The National Cancer Registry, Kenya Medical Research Institute, Nairobi, Kenya. 25. Liguanea Family Dental Centre, Seymour Park, Kingston, Jamaica; African Caribbean Cancer Consortium USA. 26. Department of Epidemiology, Mailman School of Public Health, Columbia University Irving Medical Center, New York, USA; African Caribbean Cancer Consortium USA. 27. Univ Rennes, Inserm, EHESP, Irset (Institut de recherche en santé, environnement et travail) - UMR_S 1085, Pointe-à-Pitre, Guadeloupe, France; African Caribbean Cancer Consortium USA. 28. Nigerian National System of Cancer Registries, Federal Ministry of Health, Abuja, Nigeria; Center for Big Data Research in Health, University of New South Wales, Sydney, Australia; African Caribbean Cancer Consortium USA. 29. Nigerian National System of Cancer Registries, Federal Ministry of Health, Abuja, Nigeria; Department of Anatomic Pathology, Ekiti State University and Teaching Hospital, Ado-Ekiti, Nigeria. 30. Nigerian National System of Cancer Registries, Federal Ministry of Health, Abuja, Nigeria; Abuja Cancer Registry, Department of Haematology and Blood Transfusion, University of Abuja Teaching Hospital, Gawgwalada, Nigeria. 31. Guadeloupe Cancer Registry, University Hospital of Guadeloupe, Pointe-à-Pitre, Guadeloupe, France. 32. Nigerian National System of Cancer Registries, Federal Ministry of Health, Abuja, Nigeria; Department of Pathology, Federal Medical Centre, Yola, Nigeria. 33. African Caribbean Cancer Consortium USA. 34. Dental Department, Katutura State Hospital, Windhoek, Namibia; African Caribbean Cancer Consortium USA.
Abstract
BACKGROUND: Africa and the Caribbean are projected to have greater increases in Head and neck cancer (HNC) burden in comparison to North America and Europe. The knowledge needed to reinforce prevention in these populations is limited. We compared for the first time, incidence rates of HNC in black populations from African, the Caribbean and USA. METHODS: Annual age-standardized incidence rates (IR) and 95% confidence intervals (95%CI) per 100,000 were calculated for 2013-2015 using population-based cancer registry data for 14,911 HNC cases from the Caribbean (Barbados, Guadeloupe, Trinidad & Tobago, N = 443), Africa (Kenya, Nigeria, N = 772) and the United States (SEER, Florida, N = 13,696). We compared rates by sub-sites and sex among countries using data from registries with high quality and completeness. RESULTS: In 2013-2015, compared to other countries, HNC incidence was highest among SEER states (IR: 18.2, 95%CI = 17.6-18.8) among men, and highest in Kenya (IR: 7.5, 95%CI = 6.3-8.7) among women. Nasopharyngeal cancer IR was higher in Kenya for men (IR: 3.1, 95%CI = 2.5-3.7) and women (IR: 1.5, 95%CI = 1.0-1.9). Female oral cavity cancer was also notably higher in Kenya (IR = 3.9, 95%CI = 3.0-4.9). Blacks from SEER states had higher incidence of laryngeal cancer (IR: 5.5, 95%CI = 5.2-5.8) compared to other countries and even Florida blacks (IR: 4.4, 95%CI = 3.9-5.0). CONCLUSION: We found heterogeneity in IRs for HNC among these diverse black populations; notably, Kenya which had distinctively higher incidence of nasopharyngeal and female oral cavity cancer. Targeted etiological investigations are warranted considering the low consumption of tobacco and alcohol among Kenyan women. Overall, our findings suggest that behavioral and environmental factors are more important determinants of HNC than race.
BACKGROUND: Africa and the Caribbean are projected to have greater increases in Head and neck cancer (HNC) burden in comparison to North America and Europe. The knowledge needed to reinforce prevention in these populations is limited. We compared for the first time, incidence rates of HNC in black populations from African, the Caribbean and USA. METHODS: Annual age-standardized incidence rates (IR) and 95% confidence intervals (95%CI) per 100,000 were calculated for 2013-2015 using population-based cancer registry data for 14,911 HNC cases from the Caribbean (Barbados, Guadeloupe, Trinidad & Tobago, N = 443), Africa (Kenya, Nigeria, N = 772) and the United States (SEER, Florida, N = 13,696). We compared rates by sub-sites and sex among countries using data from registries with high quality and completeness. RESULTS: In 2013-2015, compared to other countries, HNC incidence was highest among SEER states (IR: 18.2, 95%CI = 17.6-18.8) among men, and highest in Kenya (IR: 7.5, 95%CI = 6.3-8.7) among women. Nasopharyngeal cancer IR was higher in Kenya for men (IR: 3.1, 95%CI = 2.5-3.7) and women (IR: 1.5, 95%CI = 1.0-1.9). Female oral cavity cancer was also notably higher in Kenya (IR = 3.9, 95%CI = 3.0-4.9). Blacks from SEER states had higher incidence of laryngeal cancer (IR: 5.5, 95%CI = 5.2-5.8) compared to other countries and even Florida blacks (IR: 4.4, 95%CI = 3.9-5.0). CONCLUSION: We found heterogeneity in IRs for HNC among these diverse black populations; notably, Kenya which had distinctively higher incidence of nasopharyngeal and female oral cavity cancer. Targeted etiological investigations are warranted considering the low consumption of tobacco and alcohol among Kenyan women. Overall, our findings suggest that behavioral and environmental factors are more important determinants of HNC than race.
Authors: Camille Ragin; Elizabeth Blackman; Robin Roberts; Raleigh Butler; Samuel Gathere; Darron Halliday; Kimlin Ashing Journal: Cancer Causes Control Date: 2017-11 Impact factor: 2.506
Authors: Diana Menya; Stephen K Maina; Caroline Kibosia; Nicholas Kigen; Margaret Oduor; Fatma Some; David Chumba; Paul Ayuo; Daniel R S Middleton; Odipo Osano; Behnoush Abedi-Ardekani; Joachim Schüz; Valerie A McCormack Journal: Int J Cancer Date: 2019-01-12 Impact factor: 7.396
Authors: Adana A M Llanos; Jie Li; Jennifer Tsui; Joseph Gibbons; Karen Pawlish; Fechi Nwodili; Shannon Lynch; Camille Ragin; Antoinette M Stroup Journal: Front Oncol Date: 2022-04-08 Impact factor: 5.738