| Literature DB >> 34739415 |
Jiren Sun1, Marcelo Coca Perraillon2, Rebecca Myerson1.
Abstract
BACKGROUND: Annual lung cancer screening via low-dose computed tomography can reduce lung cancer mortality among high-risk adults by 20%; however, screening take-up remains low. Inadequate insurance coverage or access to care may be a barrier to screening.Entities:
Mesh:
Year: 2022 PMID: 34739415 PMCID: PMC8663516 DOI: 10.1097/MLR.0000000000001655
Source DB: PubMed Journal: Med Care ISSN: 0025-7079 Impact factor: 2.983
Summary Statistics for People at High Risk for Lung Cancer
| Raw # of Patients | ||||
|---|---|---|---|---|
| Characteristics | Men (n=3504) | Women (n=3056) |
| SMD |
| Ages 56–64 | ||||
| Age [median (IQR)] (y) | 60 (4) | 60 (4) | 0.27 | 0.027 |
| Race/ethnicity | ||||
| Non-Hispanic White | 3055 (85.4) | 2681 (88.7) | 0.21 | 0.039 |
| Non-Hispanic Black | 128 (7.0) | 116 (4.8) | ||
| Hispanic | 67 (3.1) | 44 (1.9) | ||
| Others | 193 (4.4) | 175 (4.6) | ||
| Income | ||||
| <$25,000 | 1153 (34.5) | 1182 (40.2) | 0.06 | 0.173 |
| $25,000 to <$50,000 | 822 (25.4) | 654 (25.2) | ||
| ≥$50,000 | 1122 (40.1) | 773 (34.6) | ||
| Employment status | ||||
| Unemployed | 211 (8.3) | 189 (12.0) | 0.007 | 0.125 |
| Employed | 1683 (67.2) | 1094 (58.2) | ||
| Retired | 680 (24.5) | 558 (29.7) | ||
| Education | ||||
| College-educated | 1507 (39.1) | 1497 (42.5) | 0.17 | 0.122 |
| Non–college-educated | 1991 (60.9) | 1550 (57.5) | ||
| Veteran status | ||||
| Veteran | 979 (26.5) | 125 (4.3) | <0.001 | 0.689 |
| Nonveteran | 2517 (73.5) | 2930 (95.7) | ||
| Health insurance status | ||||
| Insured | 3030 (88.1) | 2729 (89.3) | 0.45 | 0.088 |
| Uninsured | 462 (11.9) | 317 (10.7) | ||
| State’s Medicaid expansion status | ||||
| Expanded | 1722 (40.7) | 1529 (43.2) | 0.29 | 0.018 |
| Not expanded | 1782 (59.3) | 1527 (56.8) | ||
| Ever diagnosed with COPD | ||||
| Yes | 1027 (26.3) | 1210 (41.6) | <0.001 | 0.216 |
| No | 2441 (73.7) | 1826 (58.4) | ||
| Ever diagnosed with asthma | ||||
| Yes | 448 (11.6) | 730 (24.7) | <0.001 | 0.290 |
| No | 3039 (88.4) | 2314 (75.3) | ||
| Having personal doctor(s) or health care provider(s) | ||||
| Yes | 2873 (81.6) | 2736 (89.7) | <0.001 | 0.214 |
| No | 622 (18.4) | 317 (10.3) | ||
| Routine checkup within the past year | ||||
| Yes | 2669 (78.2) | 2484 (83.3) | 0.006 | 0.122 |
| No | 794 (21.8) | 546 (16.7) | ||
| Skipping care because of costs in the past 12 mo | ||||
| Yes | 562 (16.6) | 598 (19.7) | 0.09 | 0.093 |
| No | 2932 (83.4) | 2444 (80.3) | ||
| Having a CT or CAT scan in the last 12 mo | ||||
| Yes | 414 (12.6) | 428 (15.8) | 0.07 | 0.067 |
| No | 3040 (87.4) | 2575 (84.2) | ||
Weighted percentages were estimated using data from Behavioral Risk Factor Surveillance System (BRFSS) 2017–2019. Percentages have been rounded and may not total 100.
P-value for age is from the Wilcoxon rank-sum test, and P-values for other characteristics are from the χ2 test.
COPD indicates chronic obstructive pulmonary disease; CT/CAT, computed tomography; IQR, interquartile range; SMD, standardized mean difference.
FIGURE 1Health insurance coverage among men and women at high risk for lung cancer, above and below age 65. These graphs show the proportion of people at high risk for lung cancer who report currently having health insurance coverage. Age 65 is the age of nearly universal access to Medicare coverage. The scatterplots were fit separately by sex, above and below this age cutoff. Data are from Behavioral Risk Factor Surveillance System (BRFSS) 2017–2019.
Changes in Health Insurance Coverage and Lung Cancer Screening at Age 65: A RD Analysis
| Men | Women | |||||
|---|---|---|---|---|---|---|
| Age 63–64 | RD at Age 65 | Age 63–64 | RD at Age 65 | |||
| Outcome | Baseline | Unadjusted | Adjusted | Baseline | Unadjusted | Adjusted |
| Health insurance coverage | ||||||
| People with high lung cancer risk (meet USPSTF criteria for screening) | 90.4 | 8.7 (1.6–15.8) | 10.4 (3.6–17.2) | 90.4 | 9.4 (0.9–18.0) | 8.8 (0.1–17.5) |
| | 0.02 | 0.003 | 0.03 | 0.05 | ||
| People with lower risk (do not meet USPSTF criteria) | 91.2 | 6.0 (2.6–9.3) | 5.6 (2.3–8.8) | 92.0 | 6.1 (3.3–8.8) | 6.5 (3.9–9.2) |
| | <0.001 | <0.001 | <0.001 | <0.001 | ||
| Lung cancer screening | ||||||
| People with high lung cancer risk (meet USPSTF criteria for screening) | 11.1 | 14.8 (0.7–28.9) | 16.2 (2.4–30.0) | 18.2 | 2.7 (−20.0 to 25.4) | 1.6 (−19.8 to 23.0) |
| | 0.04 | 0.02 | 0.82 | 0.88 | ||
| People with lower risk (do not meet USPSTF criteria) | 4.0 | 4.3 (−0.1 to 8.6) | 3.7 (−0.5 to 8.0) | 4.5 | 3.8 (0.1–7.5) | 3.9 (0.3–7.6) |
| | 0.05 | 0.09 | 0.05 | 0.04 | ||
The columns include findings from stratified analyses, including only men or women as noted in the headlines. Models were centered at 65, so estimates apply to age 65. “Unadjusted” estimates control only for age. Models allowed age trend terms to vary above versus below the cutoff. Adjusted estimated regression discontinuities at age 65 adjusted for respondents’ age, race, employment status, income level, education level, veteran status, state of residence, state’s Medicaid expansion status, and year of the interview. 95% confidence intervals calculated using robust SEs are in parentheses.
RD indicates regression discontinuity; USPSTF, US Preventive Services Task Force.
FIGURE 2Lung cancer screening among men and women at high risk for lung cancer, above and below age 65. These graphs show the proportion of people at high risk for lung cancer who reported having a CT/CAT scan check for lung cancer in the past 12 months. Age 65 is the age of nearly universal eligibility for Medicare coverage. The scatterplots were fit separately by sex, above and below this age cutoff. Data from people who turned 65 during the 12-month look-back period (eg, who had partial exposure to nearly universal access to Medicare coverage) were excluded from the analysis. Data are from Behavioral Risk Factor Surveillance System (BRFSS) 2017–2019. CT/CAT indicates computed tomography.