| Literature DB >> 34729572 |
Lara Massai1, Silvia Ciambellotti1,2,3, Lucrezia Cosottini1,2,3, Luigi Messori1, Paola Turano1,2,3, Alessandro Pratesi4.
Abstract
Human cytoplasmic ferritins are heteropolymers of H and L subunits containing a catalytic ferroxidase center and a nucleation site for iron biomineralization, respectively. Here, ESI-MS successfully detected labile metal-protein interactions revealing the formation of tetra- and octa-iron clusters bound to L subunits, as previously underscored by X-ray crystallography.Entities:
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Year: 2021 PMID： 34729572 DOI： 10.1039/d1dt03106f
Source DB: PubMed Journal: Dalton Trans ISSN： 1477-9226 Impact factor: 4.390