Literature DB >> 3472489

Comparison of difloxacin, enoxacin, and cefoperazone for treatment of experimental Enterobacter aerogenes endocarditis.

J A Boscia, W D Kobasa, D Kaye.   

Abstract

This study compared difloxacin administered orally, enoxacin administered orally, and cefoperazone administered intramuscularly for the treatment of experimental Enterobacter aerogenes endocarditis. Difloxacin significantly reduced bacterial counts of vegetations, as compared with enoxacin and cefoperazone. Enoxacin and cefoperazone did not differ significantly. This study demonstrated that difloxacin was significantly more effective than enoxacin and cefoperazone for the treatment of E. aerogenes endocarditis in rabbits.

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Year:  1987        PMID: 3472489      PMCID: PMC174752          DOI: 10.1128/AAC.31.3.458

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN: 0066-4804            Impact factor:   5.191


  6 in total

1.  Chemotherapy of experimental streptococcal endocarditis. I. Comparison of commonly recommended prophylactic regimens.

Authors:  D T Durack; R G Petersdorf
Journal:  J Clin Invest       Date:  1973-03       Impact factor: 14.808

2.  Antibiotic synergism in enterococcal endocarditis.

Authors:  J Carrizosa; D Kaye
Journal:  J Lab Clin Med       Date:  1976-07

3.  Enoxacin compared with cefoperazone for the treatment of experimental Enterobacter aerogenes endocarditis.

Authors:  J A Boscia; W D Kobasa; D Kaye
Journal:  Antimicrob Agents Chemother       Date:  1985-05       Impact factor: 5.191

4.  The importance of pharmacodynamics in determining the dosing interval in therapy for experimental pseudomonas endocarditis in the rat.

Authors:  M J Ingerman; P G Pitsakis; A F Rosenberg; M E Levison
Journal:  J Infect Dis       Date:  1986-04       Impact factor: 5.226

5.  Comparison of ciprofloxacin with azlocillin plus tobramycin in the therapy of experimental Pseudomonas aeruginosa endocarditis.

Authors:  R W Strunk; J C Gratz; R Maserati; W M Scheld
Journal:  Antimicrob Agents Chemother       Date:  1985-09       Impact factor: 5.191

6.  Ciprofloxacin as therapy for experimental osteomyelitis caused by Pseudomonas aeruginosa.

Authors:  C W Norden; E Shinners
Journal:  J Infect Dis       Date:  1985-02       Impact factor: 5.226

  6 in total
  2 in total

Review 1.  Enoxacin. A review of its antibacterial activity, pharmacokinetic properties and therapeutic use.

Authors:  J M Henwood; J P Monk
Journal:  Drugs       Date:  1988-07       Impact factor: 9.546

Review 2.  Fluoroquinolone antimicrobial agents.

Authors:  J S Wolfson; D C Hooper
Journal:  Clin Microbiol Rev       Date:  1989-10       Impact factor: 26.132

  2 in total

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