Literature DB >> 34724625

Severe Keratitis Caused by Acanthamoeba Genotype T12 in Thailand: A Case Report.

Vannarut Satitpitakul1,2, Chaturong Putaporntip3, Somchai Jongwutiwes3.   

Abstract

Acanthamoeba keratitis is predominantly caused by genotype T4. We report a case of severe keratitis caused by Acanthamoeba in a 39-year-old man who had prior accidental exposure to a corrosive chemical. The patient developed central full thickness ring infiltration and epithelial defect with hypopyon that required keratoplasty. The acanthamoebae isolated from the patient exhibited thermotolerance phenotype with the capability to grow well at ambient temperature and at 42°C. Analysis of a near complete 18S rRNA gene of this isolate revealed a distinct sequence that can be unequivocally assigned to genotype T12, a rare genotype incriminated in corneal infections.

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Year:  2021        PMID： 34724625      PMCID： PMC8832935          DOI： 10.4269/ajtmh.21-0666

Source DB:  PubMed          Journal:  Am J Trop Med Hyg        ISSN： 0002-9637            Impact factor:   2.345


  17 in total

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5.  Identification of a novel t17 genotype of acanthamoeba from environmental isolates and t10 genotype causing keratitis in Thailand.

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Review 6.  Acanthamoeba spp. as agents of disease in humans.

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7.  Update on Acanthamoeba phylogeny.

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Review 8.  Acanthamoeba keratitis - Clinical signs, differential diagnosis and treatment.

Authors:  Nóra Szentmáry; Loay Daas; Lei Shi; Kornelia Lenke Laurik; Sabine Lepper; Georgia Milioti; Berthold Seitz
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  1 in total

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