Literature DB >> 34720149

Impact of an Interprofessional Collaborative Quality Improvement Initiative to Decrease Inappropriate Thyroid Function Testing.

Alyssa B Bradshaw1, Alex K Bonnecaze2, Cynthia A Burns2, James R Beardsley1,2.   

Abstract

Background: Published data show that thyroid function laboratory tests are often ordered inappropriately in the acute care setting, which leads to unnecessary costs and inappropriate therapy decisions. Pilot data at our institution indicated that approximately two-thirds of the thyroid-stimulating hormone (TSH) laboratories were unnecessary, correlating to a potential cost avoidance of more than $20,000 annually. The purpose of this study was to improve the appropriateness of thyroid function test ordering with a multipronged initiative. Methodology: This controlled, single-center, before and after study included inpatients or emergency department (ED) patients at Wake Forest Baptist Medical Center who were at least 18 years of age and had a TSH level ordered during the study period. Patients with a history of thyroid cancer were excluded. The initiative included an electronic ordering intervention, direct education of providers (medical residents, attendings, and clinical pharmacists), and distribution of pocket information cards with appropriate ordering criteria. The primary outcome was the number and percentage of inappropriate TSH tests ordered before and after implementing the 3 interventions. Secondary outcomes included cost savings, inappropriate changes in thyroid therapy based on improperly ordered tests, and the number of free T4 lab tests ordered on patients with a TSH within the therapeutic range.
Results: All 3 interventions were implemented, except for education of ED residents and faculty, who chose to forgo the direct education component. Inappropriate ordering of TSH levels decreased from 63 to 50 (13% reduction, P = .062) after implementation. Inappropriate TSH ordering decreased across all services, except in the ED. Inappropriate Free T4 orders decreased from 191 to 133 (30% reduction, P = .01). There were no therapy changes based on inappropriate TSH orders. Extrapolated annual cost savings were approximately $6,000.
Conclusion: This multipronged interprofessional collaborative quality improvement initiative was associated with a nonstatistically significant reduction in inappropriate TSH orders, statistically significant reduction in inappropriate free T4 orders, and cost savings. There was a reduction in inappropriate ordering across all services except the ED, which may have been due the ED not participating in the direct education component of the initiative.
© The Author(s) 2020.

Entities:  

Keywords:  TSH; cost; diagnostic stewardship; free T4; quality improvement; thyroid function laboratory tests

Year:  2020        PMID: 34720149      PMCID: PMC8554587          DOI: 10.1177/0018578720920795

Source DB:  PubMed          Journal:  Hosp Pharm        ISSN: 0018-5787


  5 in total

Review 1.  Do we know what inappropriate laboratory utilization is? A systematic review of laboratory clinical audits.

Authors:  C van Walraven; C D Naylor
Journal:  JAMA       Date:  1998-08-12       Impact factor: 56.272

2.  Changing resident test ordering behavior: a multilevel intervention to decrease laboratory utilization at an academic medical center.

Authors:  Arpana R Vidyarthi; Timothy Hamill; Adrienne L Green; Glenn Rosenbluth; Robert B Baron
Journal:  Am J Med Qual       Date:  2014-01-17       Impact factor: 1.852

3.  Factors contributing to inappropriate ordering of tests in an academic medical department and the effect of an educational feedback strategy.

Authors:  Spiros Miyakis; Georgios Karamanof; Michalis Liontos; Theodore D Mountokalakis
Journal:  Postgrad Med J       Date:  2006-12       Impact factor: 2.401

4.  A review on laboratory tests' utilization: A trigger for cutting costs and quality improvement in health care settings.

Authors:  Zahra Meidani; Mehrdad Farzandipour; Alireza Farrokhian; Masomeh Haghighat
Journal:  Med J Islam Repub Iran       Date:  2016-05-08

Review 5.  Effectiveness of interventions to reduce ordering of thyroid function tests: a systematic review.

Authors:  Zhivko Zhelev; Rebecca Abbott; Morwenna Rogers; Simon Fleming; Anthea Patterson; William Trevor Hamilton; Janet Heaton; Jo Thompson Coon; Bijay Vaidya; Christopher Hyde
Journal:  BMJ Open       Date:  2016-06-03       Impact factor: 2.692

  5 in total

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