Literature DB >> 34720018

SHISA5/SCOTIN restrains spontaneous autophagy induction by blocking contact between the ERES and phagophores.

Jee-Eun Lee1, Nari Kim1, Minkyo Jung2, Ji-Young Mun2, Joo-Yeon Yoo1.   

Abstract

ABBREVIATIONS: ATG2: autophagy related 2; BECN1: beclin 1; COPII: coat protein II; DMSO: dimethyl sulfoxide; EBSS: Earle's balanced salt solution; EGFP: enhanced green fluorescent protein; ER: endoplasmic reticulum; ERES: ER exit site(s); GFP: green fluorescent protein; H89: H-89 dihydrochloride hydrate; LAMP1: lysosomal-associated membrane protein 1; MAP1LC3/LC3: microtubule-associated protein 1 light chain 3; MTORC1: mechanistic target of rapamycin kinase complex 1; NS5A: nonstructural protein 5A; PIK3C3/VPS34: phosphatidylinositol 3-kinase catalytic subunit type 3; PLA: proximity ligation assay; PtdIns3P: phosphatidylionositol-3-phosphate; RB1CC1/FIP200: RB1 inducible coiled-coil 1; RFP: red fluorescent protein; RPS6KB1/S6K: ribosomal protein S6 kinase B1; SBP: streptavidin binding protein; SEC16A: SEC16 homolog A, endoplasmic reticulum export factor; SEC31A: SEC31 homolog A, COPII coat complex component; siRNA: small interfering RNA; Str: streptavidin; ULK1: unc-51-like autophagy activating kinase 1; VSVG: vesicular stomatitis virus glycoprotein; WIPI2: WD repeat domain, phosphoinositide interacting 2; WT: wild type.

Entities:  

Keywords:  Constitutive autophagy; SHISA5/SCOTIN; endoplasmic reticulum exit sites; membrane contact; phagophore

Mesh:

Substances:

Year:  2021        PMID: 34720018      PMCID: PMC9298459          DOI: 10.1080/15548627.2021.1994297

Source DB:  PubMed          Journal:  Autophagy        ISSN: 1554-8627            Impact factor:   13.391


  68 in total

1.  The origin of the autophagosomal membrane.

Authors:  Sharon A Tooze; Tamotsu Yoshimori
Journal:  Nat Cell Biol       Date:  2010-09       Impact factor: 28.824

2.  BlobFinder, a tool for fluorescence microscopy image cytometry.

Authors:  A Allalou; C Wählby
Journal:  Comput Methods Programs Biomed       Date:  2008-10-23       Impact factor: 5.428

3.  The EM structure of the TRAPPIII complex leads to the identification of a requirement for COPII vesicles on the macroautophagy pathway.

Authors:  Dongyan Tan; Yiying Cai; Juan Wang; Jinzhong Zhang; Shekar Menon; Hui-Ting Chou; Susan Ferro-Novick; Karin M Reinisch; Thomas Walz
Journal:  Proc Natl Acad Sci U S A       Date:  2013-11-11       Impact factor: 11.205

4.  Atg2A/B deficiency switches cytoprotective autophagy to non-canonical caspase-8 activation and apoptosis.

Authors:  Zhenyuan Tang; Yoshinori Takahashi; Chong Chen; Ying Liu; Haiyan He; Nikolaos Tsotakos; Jacob M Serfass; Melat T Gebru; Han Chen; Megan M Young; Hong-Gang Wang
Journal:  Cell Death Differ       Date:  2017-08-11       Impact factor: 15.828

5.  The ER Contact Proteins VAPA/B Interact with Multiple Autophagy Proteins to Modulate Autophagosome Biogenesis.

Authors:  Yan G Zhao; Nan Liu; Guangyan Miao; Yong Chen; Hongyu Zhao; Hong Zhang
Journal:  Curr Biol       Date:  2018-04-05       Impact factor: 10.834

6.  The Atg18-Atg2 complex is recruited to autophagic membranes via phosphatidylinositol 3-phosphate and exerts an essential function.

Authors:  Keisuke Obara; Takayuki Sekito; Kaori Niimi; Yoshinori Ohsumi
Journal:  J Biol Chem       Date:  2008-06-27       Impact factor: 5.157

Review 7.  mTOR Signaling in Growth, Metabolism, and Disease.

Authors:  Robert A Saxton; David M Sabatini
Journal:  Cell       Date:  2017-03-09       Impact factor: 41.582

8.  A cluster of thin tubular structures mediates transformation of the endoplasmic reticulum to autophagic isolation membrane.

Authors:  Takefumi Uemura; Masaya Yamamoto; Ai Kametaka; Yu-shin Sou; Atsuko Yabashi; Akane Yamada; Hiromichi Annoh; Satoshi Kametaka; Masaaki Komatsu; Satoshi Waguri
Journal:  Mol Cell Biol       Date:  2014-03-03       Impact factor: 4.272

Review 9.  Emerging roles of ATG proteins and membrane lipids in autophagosome formation.

Authors:  Taki Nishimura; Sharon A Tooze
Journal:  Cell Discov       Date:  2020-05-26       Impact factor: 10.849

10.  The autophagic membrane tether ATG2A transfers lipids between membranes.

Authors:  Shintaro Maeda; Chinatsu Otomo; Takanori Otomo
Journal:  Elife       Date:  2019-07-04       Impact factor: 8.140

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