| Literature DB >> 3471742 |
B Arce-Gomez, R A Moliterno, A L Rodrigues, J Barbosa, M R deOliveira, J C Abreu, V A SpeckdoNascimento, M G Sasaki.
Abstract
HLA-A and B phenotyping was carried out, during a viral hepatitis A (VHA) epidemic in Brazil, on 47 unrelated patients with VHA and 53 unrelated healthy subjects of the same age, sex, social status, and ethnic origin. An increased frequency of HLA-A9 (44.7% vs. 15.1%) and a decrease of that of HLA-A3 (2.1% vs. 22.6%) were observed when compared with controls. After correction for the number of antigens tested, only the positive association with HLA-A9 was observed. It was found that the relative risk for an HLA-A9 carrier to develop VHA was 4.5.Entities:
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Year: 1987 PMID: 3471742 DOI: 10.1016/0198-8859(87)90085-1
Source DB: PubMed Journal: Hum Immunol ISSN: 0198-8859 Impact factor: 2.850