Literature DB >> 3471742

Association of viral hepatitis A with HLA-A9.

B Arce-Gomez, R A Moliterno, A L Rodrigues, J Barbosa, M R deOliveira, J C Abreu, V A SpeckdoNascimento, M G Sasaki.   

Abstract

HLA-A and B phenotyping was carried out, during a viral hepatitis A (VHA) epidemic in Brazil, on 47 unrelated patients with VHA and 53 unrelated healthy subjects of the same age, sex, social status, and ethnic origin. An increased frequency of HLA-A9 (44.7% vs. 15.1%) and a decrease of that of HLA-A3 (2.1% vs. 22.6%) were observed when compared with controls. After correction for the number of antigens tested, only the positive association with HLA-A9 was observed. It was found that the relative risk for an HLA-A9 carrier to develop VHA was 4.5.

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Year:  1987        PMID: 3471742     DOI: 10.1016/0198-8859(87)90085-1

Source DB:  PubMed          Journal:  Hum Immunol        ISSN: 0198-8859            Impact factor:   2.850


  1 in total

Review 1.  A comparative review of HLA associations with hepatitis B and C viral infections across global populations.

Authors:  Rashmi Singh; Rashmi Kaul; Anil Kaul; Khalid Khan
Journal:  World J Gastroenterol       Date:  2007-03-28       Impact factor: 5.742

  1 in total

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